"Biolääketieteellisen teknologian yksikkö - Institute of Biomedical Technology" - Selaus tiedekunnan mukaan (- 2018)Opinnäytteet - ylempi korkeakoulututkinto
Viitteet 1-20 / 67
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Adipose stem cells and structural composites in the engineering of vascularized bone tissue
(2013)
Pro gradu -tutkielma -
Adult zebrafish model for studying DNA-based vaccination against mycobacterial disease
(2011)
Pro gradu -tutkielma -
Aggregation prediction; A bioinformatics method for studying the effects of missense variations on pathogenicity
(2012)
Pro gradu -tutkielmaBackground and Aims: Aggregation has been shown to be an intrinsic property of many proteins including proteins not involved in amyloid diseases. The most common types of protein aggregates are amyloid fibrils and amorphous ... -
Analysis of carbonic anhydrase related proteins VIII, X, and XI
(2011)
Pro gradu -tutkielmaBackground and Aims: Carbonic anhydrases (CAs) occur abundantly in nature and are found in many organisms which participate in many biologically important processes. Among the -CA gene family, there are three homologues ... -
Analysis of evolutionary pressure and pathogenicity of missense variations
(2012)
Pro gradu -tutkielmaBackground and aims: Gene and protein sequences are subject to variation upon reproduction where favorable alleles are expressed in further generations by positive selection and bad alleles are being eliminated by means ... -
Analysis of nucleotide repeats at variation sites
(2012)
Pro gradu -tutkielmaAbstract Background and aims:Nucleotide repeats are sequences that are repeated two or more times in the genome. They are generally classified into two broad groups as tandem repeats or dispersed repeats. They can be found ... -
Analysis of regulated genes of BMP4 signaling in breast cancer cell lines
(2013)
Pro gradu -tutkielmaBackground and aim: The role of bone morphogenetic proteins (BMP) 4 and 7 in primary breast cancer is peculiar as they are known to induce cell proliferation in some tumor cells and also to reduce tumor growth in some ... -
Analysis of variation site in post-translational modification
(2013)
Pro gradu -tutkielmaPost-translational modification (PTM) is a modification of a protein after its translation. This modification can occur either by the covalent addition of particular chemical groups or by enzymatic cleavage of peptide bond. ... -
Applying genome-wide approach to define the genetics of low-density lipoprotein oxidation in two large cohorts
(2013)
Pro gradu -tutkielmaBackground: Cardiovascular diseases (CVD) are the number one killer and cause of disability in today’s world. Oxidized low-density lipoprotein (oxLDL) is considered to be a key factor in the development of atherosclerosis ... -
B-Trikalsiumfosfaattia (B-TCP) sisältävän, antibiootteja vapauttavan ja biohajoavan luun täytemateriaalin ominaisuuksien tutkimus
(2011)
Pro gradu -tutkielmaTutkimuksen tausta ja tavoitteet: Osteomyeliitti eli luumätä on bakteerien aiheuttama luukudoksen tuhoutumistauti, jossa patogeenejä on vaikea tuhota ja jonka jättämiä vaurioita voidaan nykyään etupäässä hoitaa luusiirteillä ... -
Bioaktiivisten tripeptidien (IPP ja VPP) vaikutus ihmisen verisuonitonusta sääteleviin entsyymeihin ACE1, eNOS ja COX-2 napanuoran laskimon endoteelisoluissa (HUVEC)
(2011)
Pro gradu -tutkielmaTausta ja tavoitteet: Kohonnut verenpaine on vakava terveysongelma, johon nykytiedon mukaan voidaan vaikuttaa bioaktiivisia tripeptidejä (IPP ja VPP) sisältävällä ruokavaliolla. Vaikutusmekanismi on toistaiseksi puutteellisesti ... -
Bioinformatic analysis of next-generation sequencing data
(2012)
Pro gradu -tutkielmaBackround and aims:In a recent linkage study involving 69 Finnish HPC (Hereditary prostate cancer) families, a novel prostate cancer susceptibility locus 2q37.3 was found (Cropp et al. 2011). In addition a signal from ... -
BMP7 as a modulator of breast cancer growth and migration
(2011)
Pro gradu -tutkielmaBackground and aims: Breast cancer is the most common cancer in women in Western countries and a global health concern affecting millions of people. Thus the search for causative agents and possible curatives continues to ... -
Brave New Avidins
(2011)
Pro gradu -tutkielmaBackground and aims: The extremely high affinity of (strep)avidin towards biotin (Kd≈10-15-10-16) and stability enables its use in a variety of applications; for example, in targeted drug therapy, affinity chromatography ... -
Characterization of Pathogenic mutations in Kinase domain
(2013)
Pro gradu -tutkielmaBackground and aims:Protein Kinases having significant effects on signal transduction as well as most of the cellular processes, frequently causes diseases. A large number of disease-causing mutations have been recognized ... -
Cloning of UBAP2 and its role in prostate cancer
(2013)
Pro gradu -tutkielmaBackground and aims: Prostate cancer is a common malignancy affecting millions of men worldwide. The molecular mechanisms involved in prostate cancer are poorly understood. Genomic copy-number alterations are common in ... -
Comparison of Temperature Coupling Algorithms in SMD simulations and Mutation Design in Talin I/LWEQ Domain
(2013)
Pro gradu -tutkielmaRecently, a significant number of studies regarding the activation mechanism of talin's vinculin binding site (VBS) have been published. Since the hydrophobic VBS is in natural talin buried inside the helix structure, a ... -
Concordance between Pathway Databases and Refinement of Pathways for Computational Analysis
(2012)
Pro gradu -tutkielmaTutkimuksen tausta ja tavoitteet: Biologiassa tutkimus suuntautuu kokoajan kohti systeemitason tutkimusta. Enää ei tutkita vain yhtä tai muutamaa geeniä, vaan keskitytään kokonaisuuteen, jossa ne esiintyvät. Signalointireitit ... -
Development of a Protein Conservation Analysis Pipeline and Application to Carbonic Anhydrase IV
(2013)
Pro gradu -tutkielma*Background and Aims * Conservation is a hallmark of inherent valuable function. Computational analysis of conservation of each amino acid in a protein provides targets for future computational or experimental research. ... -
Development of a serotype-specific detection method for the diabetogenic coxsackievirus B1
(2012)
Pro gradu -tutkielma