"BioMediTech - BioMediTech" - Selaus tiedekunnan mukaan (- 2018)Opinnäytteet - ylempi korkeakoulututkinto
Viitteet 1-20 / 57
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A Comparative Analysis of Thermodynamic Stability of Electron transport Chain Complex I Proteins and the Maximum Life Span of Host Organisms
(2014)
Pro gradu -tutkielmaBackground and Aims: "Mitochondrial theory of ageing" is an established theory which states that there is a correlation between Maximum Life Span (MLSP) of an organism and its mitochondrial free radical production. Here ... -
A new method for long-term culturing of intestinal biopsies derived from Celiac Disease patients using mice as carriers
(2016)
Pro gradu -tutkielmaCeliac disease (CD) is a complex disorder with no bona fide animal model that would exhibit all the features of the disorder. The small-intestinal mucosal biopsies commonly used to study the disease present a limiting ... -
A pipeline to optimize metabolic pathways in the synthetically regulated Saccharomyces cerevisiae using tryptophan pathway as an example
(2016)
Pro gradu -tutkielmaBackground and aims: Cell factories are currently used to produce biochemicals for nutrition, pharma, medical, and energy industries with a high future potential and interest among these and other industries. General ... -
Activation of Intracellular Signalling Pathways in Adipose Stem Cell- mediated Immunosuppression
(2016)
Pro gradu -tutkielmaBackground and aims: Adipose tissue is a source of multipotent adipose stromal/stem cells (ASCs). ASCs have excellent proliferation and multilineage differentiation capacity, low immunogenicity and promising immunosuppressive ... -
Allergic asthma and rhinovirus infections in a birth cohort study in Finland and Estonia
(2016)
Pro gradu -tutkielma -
Bacillus Calmette Guérin and Infection Biomarkers In Mycobacterium marinum-infected Zebrafish
(2014)
Pro gradu -tutkielma -
Background and specific contrast enhancements for imaging biological samples with micro-computational tomography
(2014)
Pro gradu -tutkielmaBackground and aims: Typically, an X-ray image forms as the applied ray becomes attenuated by the imaged sample. In biological and biomaterial samples, the common imaging issue is the low density and its homogeneous ... -
BMP4-induced microRNAs in breast cancer cell lines
(2015)
Pro gradu -tutkielmaBackground and aims: Breast cancer is the leading cause of mortality in women worldwide. In cancer, deregulation of signaling pathways, such as of the growth factor BMP4, is a common phenomenon. BMP4 is known to have a ... -
Capture of hydrocortisone binding avidins from a combinatorial library based on chicken avidin scaffold
(2015)
Pro gradu -tutkielma -
Catalytic mechanism for reduction of bicarbonate in the active site of formate dehydrogenase
(2016)
Pro gradu -tutkielmaFormate dehydrogenases (FDHs) are a set of mostly homodimeric oxidoreductases that catalyze the oxidation of formate to carbon dioxide with the concurrent reduction of NAD+ to NADH. These enzymes are common to methylotropic ... -
Characterisation of dopamine neurons of the murine ventral tegmental area in primary culture and acute dissociations
(2014)
Pro gradu -tutkielmaDopamine (DA) neurons play pivotal roles in the regulation of motor and endocrine functions, as well as affective and cognitive behaviours. The degeneration and dysregulation of these neurons has been linked to the ... -
Characterization of in vitro outer blood retinal barrier model
(2015)
Pro gradu -tutkielmaBackground and aims: The human eye has anatomically closed structure, due to the blood retinal barrier (BRB) which is protecting the photoreceptor cells. It comprises of three layers: retinal pigment epithelial cells ... -
Characterization of the protease phenotype of cultured human mast cells during their differentiation and maturation
(2015)
Pro gradu -tutkielmaABSTRACT Background and Aims: Mast cells (MCs) are tissue-dwelling effector cells of innate and adaptive immunity that differentiate in peripheral tissues from committed circulating progenitor cells of bone marrow origin. ... -
Co-culture of corneal epithelial cells and adipose stem cells - towards the use of hydrogels in ocular surface reconstruction
(2016)
Pro gradu -tutkielmaObjectives: In a tissue engineering field, co-culture techniques of different kind have been widely researched in recent years to form physiologically relevant cell structures for different tissue reconstructions. The ... -
Comparison of snv genotyping sensitivity of next-generation sequencing with illumina's miseq and quantitative real-time pcr with fluidigm's biomark hd
(2016)
Pro gradu -tutkielmaYhden nukleotidin variantti-genotyypitys (SNV-genotyypitys) on menetelmä, jota voisi soveltaa rutiininomaisesti syöpä-diagnostiikassa. Sitä ei käytetä, koska teknologiat joita menetelmä hyödyntää ovat suhteellisen uusia. ... -
Computational functional prediction of novel long noncoding RNA in TCGA Glioblastoma multiforme sample
(2016)
Pro gradu -tutkielmaAccording to international human genome sequencing consortium 2004[43], it was known that only less than 2% of the total human genome code for proteins. This ignited quite a surprise in the scientific community. Since then, ... -
Culturing human embryonic stem cell -derived neural cells in microfluidic polydimethylsiloxane structures
(2015)
Pro gradu -tutkielma -
Defining Lists of Conserved Amino Acid Residues in Alpha Carbonic Anhydrases
(2014)
Pro gradu -tutkielma