"BioMediTech - BioMediTech" - Selaus tiedekunnan mukaan (- 2018)Opinnäytteet - ylempi korkeakoulututkinto
Viitteet 21-40 / 57
-
Development of a tool for copy number analysis of cancer genomes using high throughput sequencing data
(2015)
Pro gradu -tutkielmaGenomic copy number alterations (CNA) and loss of heterozygozity (LOH) are two types of genomic instabilities associated with cancer. Acquisition of these genomic instabilities affects the expression level of oncogenes and ... -
Development of CAbase and an Exon Analysis Pipeline for Visual Assessment of Predicted Genes for the Carbonic Anhydrases
(2016)
Pro gradu -tutkielmaBackground and Aims Humans are able to quickly recognize and evaluate visual patterns, thus this thesis aims to apply this feature to the analysis of aspects of the conservation of carbonic anhydrase proteins. This was ... -
Differentiation Potential of the Human Adipose Stem Cells in Response to Regulation of ROCK, FAK and MEK-ERK Signaling Pathways
(2015)
Pro gradu -tutkielmaBackground and aims: Adipose stem cells (ASCs), obtained from adipose tissue, are a promising cell source for bone tissue engineering applications. ASCs exhibit stable growth and proliferation in vitro and they possess ... -
Dual codon usage in germline variants of prostate cancer genomes
(2015)
Pro gradu -tutkielmaThis thesis work builds on the recent discovery by Stergachis and his colleagues, which describes the process the genome uses to write genetic code. This work extends the previous vision in genome research, which states, ... -
Effects of uniaxial strain in hypertrophic cardiomyopathy -patient specific human induced pluripotent stem cell -derived cardiomyocytes
(2014)
Pro gradu -tutkielmaBackground and aims: Hypertrophic cardiomyopathy (HCM) is genetically inherited autosomal-dominant disease with significant genotypic and phenotypic heterogeneity. HCM is one of the most common inherited cardiovascular ... -
Epigenetic Polycomb signalling in Caco2 intestinal differentiation model
(2015)
Pro gradu -tutkielma -
Evaluation of the pluripotency of human induced pluripotent stem cells (hiPSCs) reprogrammed with integrative and non-integrative protocols and their differentiation into cardiomyocytes
(2014)
Pro gradu -tutkielmaResearch background and aims: The purpose of this research was to evaluate the pluripotency of integrative retro and non-integrative Sendai virally generated human induced pluripotent stem cells (hiPSCs) and their cardiac ... -
Finding SNP-markers applicable for B.rapa genotyping using high-throughput sequencing data
(2015)
Pro gradu -tutkielma -
Functional effects of SKIL overexpression in prostate cancer cell lines
(2015)
Pro gradu -tutkielmaBackground and aims: Prostate cancer is among the most common malignancies in the world affecting millions of men worldwide. Molecular mechanisms behind the prostate cancer are still poorly understood. Genomic copy-number ... -
HER-2/HER-3 dimerization and HER-3 point mutations in breast cancer
(2014)
Pro gradu -tutkielmaBreast cancer is a common disease and an important cause of mortality in women. Breast cancer has been extensively studied during the last few decades, which has led to the development of potent drugs and to the identification ... -
Homology modeling and docking study of Danio rerio Carbonic Anhydrase VI - Pentraxin protein and bioinformatics analysis of extra-cellular CAs
(2015)
Pro gradu -tutkielmaBackground and Aims Computational prediction and protein structure modeling are the marvelous inventions of computer sciences that have come to the rescue of various biological problems. The technology has revolutionized ... -
Identification of idh1 mutation-related gene signature of glioblastoma multiforme
(2014)
Pro gradu -tutkielmaBackground: Glioblastoma multiforme (GBM) is a type of commonly occurred malignant astrocytoma with an extremely poor prognosis. GBMs display a remarkable genetic variability, and it is essential to study the genomic ... -
Immunomodulation of Latent Tuberculosis in the Adult Zebrafish Infection Model
(2014)
Pro gradu -tutkielmaLatentin tuberkuloosin immunomodulaatio aikuisen seeprakalan infektiomallissa Tutkimuksen tausta: Piilevä tuberkuloosi on erittäin yleinen infektio ja epäilläänkin, että jopa kolmasosa ihmispopulaatiosta kantaa ... -
Impact of BMP-2 releasing scaffolds on human adipose stem cell differentiation
(2016)
Pro gradu -tutkielmaHuman adipose tissue is a good source of mesenchymal (adipose) stem cells which can be used in bone tissue engineering both in studying differentiation and for treating patients. Bone morphogenetic protein 2 (BMP-2) is ... -
Improving the biocompatibility of stainless steel surfaces through silane polyethylene glycol coatings
(2014)
Pro gradu -tutkielmaIn biological environments nonspecific accumulation of organic material to surfaces is often inevitable. Generally, it is also considered harmful as it, for instance, increases the risk of pathological contaminations in ... -
Interactions between estrogen and bone morphogenetic proteins in breast cancer cells
(2016)
Pro gradu -tutkielmaBackground and aims: Breast cancer is the second most common cancer in the world after lung cancer, and the most common cancer among women. The risk factors for breast cancer include different hormonal factors and consequently, ... -
Investigation of migration and spreading of cells expressing modified talin1 forms
(2014)
Pro gradu -tutkielmaFokaaliadheesiot (FA) ovat suuria, useiden proteiinien muodostamia komplekseja. Solut käyttävät adheesioita vuorovaikuttaakseen ympäristönsä sekä muiden solujen kanssa ja niiden avulla solut pystyvät mm. liikkumaan. Yksi ... -
Luun morfogeneettisen proteiini 4:n vaikutukset rinta- ja haimasyöpäsolujen kasvuun ja proteiiniekspressioon kolmiulotteisessa kasvatuksessa
(2014)
Pro gradu -tutkielmaTutkimuksen tausta ja tavoitteet: Rintasyöpä on naisten yleisin syöpätyyppi Suomessa ja maailmalla. Haimasyöpä on rintasyöpää huomattavasti harvinaisempi syöpätyyppi, mutta siihen liittyvä kuolleisuus lähentelee 100 %. ... -
Lytic Epstein-Barr virus infection in patients with rheumatoid arthritis
(2016)
Pro gradu -tutkielma
