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Expression of sterol regulatory element-binding transcription factor (SREBF) 2 and SREBF cleavage-activating protein (SCAP) in human atheroma and the association of their allelic variants with sudden cardiac death

Yue-Mei, Fan; Karhunen, Pekka J; Levula, Mari; Ilveskoski, Erkki; Mikkelsson, Jussi; Kajander, Olli A; Järvinen, Otso; Oksala, Niku; Thusberg, Janita; Vihinen, Mauno; Salenius, Juha-Pekka; Kytömäki, Leena; Soini, Juhani T; Laaksonen, Reijo; Lehtimäki, Terho (2008)
article

Background Disturbed cellular cholesterol homeostasis may lead to accumulation of cholesterol in human atheroma plaques. Cellular cholesterol homeostasis is controlled by the sterol regulatory element-binding transcription ...