"Wahlfors, Tiina" - Selaus tekijän mukaan Artikkelit
Viitteet 1-9 / 9
-
ARLTS1 and Prostate Cancer Risk - Analysis of Expression and Regulation
(2013)
articleProstate cancer (PCa) is a heterogeneous trait for which several susceptibility loci have been implicated by genome-wide linkage and association studies. The genomic region 13q14 is frequently deleted in tumour tissues of ... -
Assessing interactions of two loci (rs4242382 and rs10486567) in familial prostate cancer : statistical evaluation of epistasis
(2014)
articleUnderstanding the impact of multiple genetic variants and their interactions on the disease penetrance of familial multiple prostate cancer is very relevant to the overall understanding of carcinogenesis. We assessed the ... -
Atlas of prostate cancer heritability in European and African-American men pinpoints tissue-specific regulation
(2016)
articleAlthough genome-wide association studies have identified over 100 risk loci that explain ~33% of familial risk for prostate cancer (PrCa), their functional effects on risk remain largely unknown. Here we use genotype data ... -
Fine-mapping the 2q37 and 17q11.2-q22 loci for novel genes and sequence variants associated with a genetic predisposition to prostate cancer
(2015)
articleThe 2q37 and 17q12-q22 loci are linked to an increased prostate cancer (PrCa) risk. No candidate gene has been localized at 2q37 and the HOXB13 variant G84E only partially explains the linkage to 17q21-q22 observed in ... -
Microseminoprotein-Beta Expression in Different Stages of Prostate Cancer
(2016)
articleMicroseminoprotein-beta (MSMB, MSMB) is an abundant secretory protein contributed by the prostate, and is implicated as a prostate cancer (PC) biomarker based on observations of its lower expression in cancerous cells ... -
MiRNA Profiles in Lymphoblastoid Cell Lines of Finnish Prostate Cancer Families
(2015)
articleBACKGROUND: Heritable factors are evidently involved in prostate cancer (PrCa) carcinogenesis, but currently, genetic markers are not routinely used in screening or diagnostics of the disease. More precise information ... -
NMD and microRNA expression profiling of the HPCX1 locus reveal MAGEC1 as a candidate prostate cancer predisposition gene
(2011)
articleBackground Several predisposition loci for hereditary prostate cancer (HPC) have been suggested, including HPCX1 at Xq27-q28, but due to the complex structure of the region, the susceptibility gene has not yet been ... -
PALB2 variants in hereditary and unselected Finnish Prostate cancer cases
(2009)
articleBackground PALB2 1592delT mutation is associated with increased breast cancer and suggestive prostate cancer (PRCA) risk in Finland. In this study we wanted to assess if any other PALB2 variants associate to increased ...
