Artikkelit - Trepo

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HER-2 positive breast cancer: decreasing proportion but stable incidence in Finnish population from 1982 to 2005

Köninki, Katri; Tanner, Minna; Auvinen, Anssi; Isola, Jorma (2009)
article

Introduction Classification of breast cancers according to the HER-2 oncogene status is of central importance in the selection of post-surgical therapies. A decrease in the proportion of HER-2-positive breast cancer has ...
Trastuzumab-DM1 causes tumour growth inhibition by mitotic catastrophe in trastuzumab-resistant breast cancer cells in vivo

Barok, Mark; Tanner, Minna; Köninki, Katri; Isola, Jorma (2011)
article

Introduction Trastuzumab is widely used for the treatment of HER2-positive breast cancer. Despite encouraging clinical results, a significant fraction of patients are, or become, refractory to the drug. To overcome this, ...