"Ilmarinen, Pinja" - Selaus tekijän mukaan Artikkelit
Viitteet 1-14 / 14
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Age-specific incidence of allergic and non-allergic asthma
(2020)
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Emerging Comorbidities in Adult Asthma: Risks, Clinical Associations, and Mechanisms
(2016)
articleAsthma is a heterogeneous disease with many phenotypes, and age at disease onset is an important factor in separating the phenotypes. Most studies with asthma have been performed in patients being otherwise healthy. However, ... -
Mitochondria in the centre of human eosinophil apoptosis and survival
(2014)
articleEosinophils are abundantly present in most phenotypes of asthma and they contribute to the maintenance and exacerbations of the disease. Regulators of eosinophil longevity play critical roles in determining whether eosinophils ... -
Phenotypes, Risk Factors, and Mechanisms of Adult-Onset Asthma
(2015)
articleAsthma is a heterogeneous disease with many phenotypes, and age at disease onset is an important factor in separating the phenotypes. Genetic factors, atopy, and early respiratory tract infections are well-recognized factors ... -
Regulation of spontaneous eosinophil apoptosis - a neglected area of importance
(2014)
articleAsthma is characterized by the accumulation of eosinophils in the airways in most phenotypes. Eosinophils are inflammatory cells that require an external survival-prolonging stimulus such as granulocyte macrophage-colony ... -
Tumour necrosis factor-α regulates human eosinophil apoptosis via ligation of TNF-receptor 1 and balance between NF-κB and AP-1
(2014)
articleEosinophils play a central role in asthma. The present study was performed to investigate the effect of tumour necrosis factor-α (TNF-α) on longevity of isolated human eosinophils. In contrast to Fas, TNF-α inhibited ...
