Haku
Viitteet 1-10 / 56
The evolution and function of the minimal mitochondrial DNA replisome
(2014)
Pro gradu -tutkielma
Pro gradu -tutkielma
Characterization of in vitro outer blood retinal barrier model
(2015)
Pro gradu -tutkielma
Pro gradu -tutkielma
Background and aims: The human eye has anatomically closed structure, due to the blood retinal barrier (BRB) which is protecting the photoreceptor cells. It comprises of three layers: retinal pigment epithelial cells ...
Identification of idh1 mutation-related gene signature of glioblastoma multiforme
(2014)
Pro gradu -tutkielma
Pro gradu -tutkielma
Background: Glioblastoma multiforme (GBM) is a type of commonly occurred malignant astrocytoma with an extremely poor prognosis. GBMs display a remarkable genetic variability, and it is essential to study the genomic ...
Effects of uniaxial strain in hypertrophic cardiomyopathy -patient specific human induced pluripotent stem cell -derived cardiomyocytes
(2014)
Pro gradu -tutkielma
Pro gradu -tutkielma
Background and aims: Hypertrophic cardiomyopathy (HCM) is genetically inherited autosomal-dominant disease with significant genotypic and phenotypic heterogeneity. HCM is one of the most common inherited cardiovascular ...
A Comparative Analysis of Thermodynamic Stability of Electron transport Chain Complex I Proteins and the Maximum Life Span of Host Organisms
(2014)
Pro gradu -tutkielma
Pro gradu -tutkielma
Background and Aims: "Mitochondrial theory of ageing" is an established theory which states that there is a correlation between Maximum Life Span (MLSP) of an organism and its mitochondrial free radical production. Here ...
Evaluation of the pluripotency of human induced pluripotent stem cells (hiPSCs) reprogrammed with integrative and non-integrative protocols and their differentiation into cardiomyocytes
(2014)
Pro gradu -tutkielma
Pro gradu -tutkielma
Research background and aims: The purpose of this research was to evaluate the pluripotency of integrative retro and non-integrative Sendai virally generated human induced pluripotent stem cells (hiPSCs) and their cardiac ...
Characterisation of dopamine neurons of the murine ventral tegmental area in primary culture and acute dissociations
(2014)
Pro gradu -tutkielma
Pro gradu -tutkielma
Dopamine (DA) neurons play pivotal roles in the regulation of motor and endocrine functions, as well as affective and cognitive behaviours. The degeneration and dysregulation of these neurons has been linked to the ...
Bacillus Calmette Guérin and Infection Biomarkers In Mycobacterium marinum-infected Zebrafish
(2014)
Pro gradu -tutkielma
Pro gradu -tutkielma