Haku
Viitteet 1-10 / 51
Luun morfogeneettisen proteiini 4:n vaikutukset rinta- ja haimasyöpäsolujen kasvuun ja proteiiniekspressioon kolmiulotteisessa kasvatuksessa
(2014)
Pro gradu -tutkielma
Pro gradu -tutkielma
Tutkimuksen tausta ja tavoitteet: Rintasyöpä on naisten yleisin syöpätyyppi Suomessa ja maailmalla. Haimasyöpä on rintasyöpää huomattavasti harvinaisempi syöpätyyppi, mutta siihen liittyvä kuolleisuus lähentelee 100 %. ...
Evaluation of the pluripotency of human induced pluripotent stem cells (hiPSCs) reprogrammed with integrative and non-integrative protocols and their differentiation into cardiomyocytes
(2014)
Pro gradu -tutkielma
Pro gradu -tutkielma
Research background and aims: The purpose of this research was to evaluate the pluripotency of integrative retro and non-integrative Sendai virally generated human induced pluripotent stem cells (hiPSCs) and their cardiac ...
Effects of uniaxial strain in hypertrophic cardiomyopathy -patient specific human induced pluripotent stem cell -derived cardiomyocytes
(2014)
Pro gradu -tutkielma
Pro gradu -tutkielma
Background and aims: Hypertrophic cardiomyopathy (HCM) is genetically inherited autosomal-dominant disease with significant genotypic and phenotypic heterogeneity. HCM is one of the most common inherited cardiovascular ...
A Comparative Analysis of Thermodynamic Stability of Electron transport Chain Complex I Proteins and the Maximum Life Span of Host Organisms
(2014)
Pro gradu -tutkielma
Pro gradu -tutkielma
Background and Aims: "Mitochondrial theory of ageing" is an established theory which states that there is a correlation between Maximum Life Span (MLSP) of an organism and its mitochondrial free radical production. Here ...
Identification of idh1 mutation-related gene signature of glioblastoma multiforme
(2014)
Pro gradu -tutkielma
Pro gradu -tutkielma
Background: Glioblastoma multiforme (GBM) is a type of commonly occurred malignant astrocytoma with an extremely poor prognosis. GBMs display a remarkable genetic variability, and it is essential to study the genomic ...
Bacillus Calmette Guérin and Infection Biomarkers In Mycobacterium marinum-infected Zebrafish
(2014)
Pro gradu -tutkielma
Pro gradu -tutkielma
Mutational analysis of non-coding genome in prostate cancer using whole genome sequencing
(2014)
Pro gradu -tutkielma
Pro gradu -tutkielma
Prostate Cancer is a lethal disease characterized as progressive and possessing distinct molecular heterogeneity during its timespan. Vast number of abnormalities has been reported till now with number of somatic mutations ...
Defining Lists of Conserved Amino Acid Residues in Alpha Carbonic Anhydrases
(2014)
Pro gradu -tutkielma
Pro gradu -tutkielma
Production and characterization of human carbonic anhydrase IX in insect cells
(2014)
Pro gradu -tutkielma
Pro gradu -tutkielma
Carbonic anhydrase IX (CA IX) is a cell surface enzyme, which catalyzes CO2 hydration. It has a function to maintain favorable pH conditions for cancer cell growth and survival. Expression of CA IX is a marker of hypoxia, ...