Haku
Viitteet 31-40 / 56
Allergic asthma and rhinovirus infections in a birth cohort study in Finland and Estonia
(2016)
Pro gradu -tutkielma
Pro gradu -tutkielma
A new method for long-term culturing of intestinal biopsies derived from Celiac Disease patients using mice as carriers
(2016)
Pro gradu -tutkielma
Pro gradu -tutkielma
Celiac disease (CD) is a complex disorder with no bona fide animal model that would exhibit all the features of the disorder. The small-intestinal mucosal biopsies commonly used to study the disease present a limiting ...
Catalytic mechanism for reduction of bicarbonate in the active site of formate dehydrogenase
(2016)
Pro gradu -tutkielma
Pro gradu -tutkielma
Formate dehydrogenases (FDHs) are a set of mostly homodimeric oxidoreductases that catalyze the oxidation of formate to carbon dioxide with the concurrent reduction of NAD+ to NADH. These enzymes are common to methylotropic ...
Peptidase Inhibitor 15 as a potential target of miR-32 and functional consequences of PI15 overexpression to PC-3 prostate cancer cell line
(2016)
Pro gradu -tutkielma
Pro gradu -tutkielma
Eturauhassyöpä on miesten yleisin syöpä länsimaissa. Syövän vaarallisuuden määrää suurelta osin sen kyky tunkeutua ympäröivään kudokseen ja lähettää etäispesäkkeitä. Eturauhassyövän leviämiseen ja metastaasiin ...
Culturing human embryonic stem cell -derived neural cells in microfluidic polydimethylsiloxane structures
(2015)
Pro gradu -tutkielma
Pro gradu -tutkielma
Capture of hydrocortisone binding avidins from a combinatorial library based on chicken avidin scaffold
(2015)
Pro gradu -tutkielma
Pro gradu -tutkielma
Optimization and characterization of human vascularized adipose tissue model
(2015)
Pro gradu -tutkielma
Pro gradu -tutkielma
Background and aims: Many adipose tissue related diseases, such as obesity and type 2 diabetes, are already worldwide epidemics. In addition to being energy storage, adipose tissue is an endocrine organ, which is in ...
Functional effects of SKIL overexpression in prostate cancer cell lines
(2015)
Pro gradu -tutkielma
Pro gradu -tutkielma
Background and aims: Prostate cancer is among the most common malignancies in the world affecting millions of men worldwide. Molecular mechanisms behind the prostate cancer are still poorly understood. Genomic copy-number ...
The application of qPCR for characterization of LQTS-specific cardiomyocytes derived from induced pluripotent stem cells
(2015)
Pro gradu -tutkielma
Pro gradu -tutkielma
Background and aims: Long QT syndrome (LQTS) is an inherent cardiac disorder causing severe arrhythmias due to mutations in cardiac ion channel genes. Four founder mutations causing LQTS have been identified from Finland ...
BMP4-induced microRNAs in breast cancer cell lines
(2015)
Pro gradu -tutkielma
Pro gradu -tutkielma
Background and aims: Breast cancer is the leading cause of mortality in women worldwide. In cancer, deregulation of signaling pathways, such as of the growth factor BMP4, is a common phenomenon. BMP4 is known to have a ...