Haku
Viitteet 31-40 / 52
Delta-6-desaturase gene polymorphism is associated with lipoprotein oxidation in vitro
(2013)
- article
Background
Oxidative modification of low-density lipoprotein (LDL) is a key event in the oxidation hypothesis of atherogenesis. We have previously shown that HDL does not protect LDL from oxidation in vitro, but is in ...
Information-Theoretic Analysis of the Dynamics of an Executable Biological Model
(2013)
- article
To facilitate analysis and understanding of biological systems, large-scale data are often integrated into models using a variety of mathematical and computational approaches. Such models describe the dynamics of the ...
Characterization of aberrant pathways across human cancers
(2013)
- article
Background
Cancer is a broad group of genetic diseases which account for millions of deaths worldwide each year. Cancers are classified by various clinical, pathological and molecular methods, but even within a ...
Neural specific knockdown of cytochrome c oxidase and rescue of deleterious phenotypes with alternative oxidase in Drosophila melanogaster
(2013)
Pro gradu -tutkielma
Pro gradu -tutkielma
*Background and aims:* Defects in mitochondrial respiratory chain produce diseases commonly referred as mitochondrial diseases. Mitochondrial diseases most often affect tissues that have high energy demands, particularly ...
Risiinitoksiinin näytteenkäsittelymenetelmät LC-MS tunnistusta varten
(2013)
Pro gradu -tutkielma
Pro gradu -tutkielma
Tutkimuksen tausta ja tavoitteet: Risiini on risiinikasvin (Ricinus communis) siemenissä esiintyvä erittäin toksinen proteiini, joka estää solujen proteiinisynteesin. Risiinitoksiinia pidetään potentiaalisena aineena ...
Role for heparanase in neural differentiation
(2013)
Pro gradu -tutkielma
Pro gradu -tutkielma
The impact of influenza A hemagglutinin glycosylations on the breadth of the humoral immune response
(2013)
Pro gradu -tutkielma
Pro gradu -tutkielma
Influenza A is a highly contagious respiratory virus whose surface protein hemagglutinin (HA) constantly obtains mutations at its five antigenic sites. These mutations occasionally lead to acquisition of new N-linked ...
Cardiomyocyte MEA Data Analysis (CardioMDA) – A Novel Field Potential Data Analysis Software for Pluripotent Stem Cell Derived Cardiomyocytes
(2013)
- article
Cardiac safety pharmacology requires in-vitro testing of all drug candidates before clinical trials in order to ensure they are screened for cardio-toxic effects which may result in severe arrhythmias. Micro-electrode ...
BMP4 inhibits the proliferation of breast cancer cells and induces an MMP-dependent migratory phenotype in MDA-MB-231 cells in 3D environment
(2013)
- article
Background
Bone morphogenetic protein 4 (BMP4) belongs to the transforming growth factor β (TGF-β) family of proteins. BMPs regulate cell proliferation, differentiation and motility, and have also been reported to be ...
Copy Number Variation Analysis in Familial BRCA1/2-Negative Finnish Breast and Ovarian Cancer
(2013)
- article
Background
Inherited factors predisposing individuals to breast and ovarian cancer are largely unidentified in a majority of families with hereditary breast and ovarian cancer (HBOC). We aimed to identify germline copy ...