Background and aims: Many adipose tissue related diseases, such as obesity and type 2 diabetes, are already worldwide epidemics. In addition to being energy storage, adipose tissue is an endocrine organ, which is in ...

Human adipose tissue is a good source of mesenchymal (adipose) stem cells which can be used in bone tissue engineering both in studying differentiation and for treating patients. Bone morphogenetic protein 2 (BMP-2) is ...

Latentin tuberkuloosin immunomodulaatio aikuisen seeprakalan infektiomallissa Tutkimuksen tausta: Piilevä tuberkuloosi on erittäin yleinen infektio ja epäilläänkin, että jopa kolmasosa ihmispopulaatiosta kantaa ...

Yhden nukleotidin variantti-genotyypitys (SNV-genotyypitys) on menetelmä, jota voisi soveltaa rutiininomaisesti syöpä-diagnostiikassa. Sitä ei käytetä, koska teknologiat joita menetelmä hyödyntää ovat suhteellisen uusia. ...

Formate dehydrogenases (FDHs) are a set of mostly homodimeric oxidoreductases that catalyze the oxidation of formate to carbon dioxide with the concurrent reduction of NAD+ to NADH. These enzymes are common to methylotropic ...

Background and aims: Prostate cancer is among the most common malignancies in the world affecting millions of men worldwide. Molecular mechanisms behind the prostate cancer are still poorly understood. Genomic copy-number ...

Genomic copy number alterations (CNA) and loss of heterozygozity (LOH) are two types of genomic instabilities associated with cancer. Acquisition of these genomic instabilities affects the expression level of oncogenes and ...