Haku
Viitteet 21-30 / 65
Altered expression of epithelial-to-mesenchymal transition proteins in extraprostatic prostate cancer
(2016)
- article
Epithelial to mesenchymal transition (EMT) of cancer cells involves loss of epithelial polarity and adhesiveness, and gain of invasive and migratory mesenchymal behaviours. EMT occurs in prostate cancer (PCa) but it is ...
Mutation-Specific Phenotypes in hiPSC-Derived Cardiomyocytes Carrying Either Myosin-Binding Protein C Or α-Tropomyosin Mutation for Hypertrophic Cardiomyopathy
(2016)
- article
Hypertrophic cardiomyopathy (HCM) is a genetic cardiac disease, which affects the structure of heart muscle tissue. The clinical symptoms include arrhythmias, progressive heart failure, and even sudden cardiac death but ...
Gene and pathway level analyses of germline DNA-repair gene variants and prostate cancer susceptibility using the iCOGS-genotyping array
(2016)
- article
Background:
Germline mutations within DNA-repair genes are implicated in susceptibility to multiple forms of cancer. For prostate cancer (PrCa), rare mutations in BRCA2 and BRCA1 give rise to moderately elevated risk, ...
Regenerative biosensor chips based on switchable mutants of avidin—A systematic study
(2016)
- article
Biotinylated bait molecules can be immobilized on biotinylated sensor chips by formation of biotin–avidin–biotin bridges which are very stable when using wild-type (strept)avidin. Stable immobilization of biotinylated baits ...
Comparison of module detection algorithms in protein networks and investigation of the biological meaning of predicted modules
(2016)
- article
Background
It is generally acknowledged that a functional understanding of a biological system can only be obtained by an understanding of the collective of molecular interactions in form of biological networks. Protein ...
Flow Cytometry-Based Classification in Cancer Research: A View on Feature Selection
(2016)
- article
In this paper, we study the problem of feature selection in cancer-related machine learning tasks. In particular, we study the accuracy and stability of different feature selection approaches within simplistic machine ...
β-Carbonic Anhydrases: Novel targets for diagnosis and treatment of parasitic infections
(Tampere University Press, 2016)
Artikkeliväitöskirja
Artikkeliväitöskirja
β-hiilihappoanhydraasit ovat uusia diagnostiikan ja hoidon kohdemolekyylejä loisinfektioissa
Hiilihappoanhydraasit (CA) ovat entsyymejä, jotka luokitellaan kuuteen eri entsyymiperheeseen: α, β, γ, δ, ζ ja η. Nämä entsyymit ...
Biomaterial substrates and transplantation materials for human embryonic stem cell derived retinal pigment epithelial cells: Biomimetic approaches for retinal tissue engineering
(Tampere University Press, 2016)
Artikkeliväitöskirja
Artikkeliväitöskirja
Verkkokalvon pigmenttiepiteeli (retinal pigment epithelium, RPE) on tiivis yksikerroksinen epiteelisolukerros, joka sijaitsee silmän takaosassa verkkokalvon ja suonikalvon välissä. RPE:llä ja sen alapuolella sijaitsevalla ...
A comprehensive repertoire of tRNA-derived fragments in prostate cancer
(2016)
- article
Prostate cancer (PCa) is the most common cancer among men in developed countries. Although its genetic background is thoroughly investigated, rather little is known about the role of small non-coding RNAs (sncRNA) in this ...