Haku
Viitteet 21-30 / 67
In vivo characterization of two novel regulators of the JAK/STAT pathway in Drosophila melanogaster
(2011)
Pro gradu -tutkielma
Pro gradu -tutkielma
Background and aims: The JAK/STAT pathway is a well-conserved signalling pathway that takes part in many developmental and functional processes in both humans and flies. In both organisms, defects in this pathway have been ...
Human liposarcoma cell line SW872 as a research tool for differentiation, adipocytokine secretion and pharmacological regulation
(2011)
Pro gradu -tutkielma
Pro gradu -tutkielma
Tutkimuksen tausta ja tavoitteet: Lihavuuden esiintyvyys on lisääntynyt niin paljon, että voidaan puhua jo epidemiasta. Viimeisen vuosikymmenen aikana on selvinnyt, että rasvakudos on myös endokriininen elin, joka erittää ...
Modeling growth of cultured neocortical neuronal networks: Comparison of the simulation tools CX3D and NETMORPH
(2011)
Pro gradu -tutkielma
Pro gradu -tutkielma
Background and aims: Development of neuronal morphology and formation of networks is an elaborate process determining the information processing capabilities of the formed network. The early phases of this process are ...
Proteomics: A tool for better understanding of celiac disease
(2011)
Pro gradu -tutkielma
Pro gradu -tutkielma
Background and aims: Celiac disease (CD) is a small intestine autoimmune disorder trigger by the ingestion of gluten containing cereals (wheat, barley and rye) in genetically predispose individuals (HLA-DQ2 or DQ8). The ...
Role for heparanase in neural differentiation
(2013)
Pro gradu -tutkielma
Pro gradu -tutkielma
The impact of influenza A hemagglutinin glycosylations on the breadth of the humoral immune response
(2013)
Pro gradu -tutkielma
Pro gradu -tutkielma
Influenza A is a highly contagious respiratory virus whose surface protein hemagglutinin (HA) constantly obtains mutations at its five antigenic sites. These mutations occasionally lead to acquisition of new N-linked ...
Feature selection for classification of single amino acid variations
(2012)
Pro gradu -tutkielma
Pro gradu -tutkielma
Genetic variations that lead to changes in amino acid sequences have the ability to cause structural and functional changes of proteins. All such variations do not show phenotypic effects, so it is important to have ...
Aggregation prediction; A bioinformatics method for studying the effects of missense variations on pathogenicity
(2012)
Pro gradu -tutkielma
Pro gradu -tutkielma
Background and Aims: Aggregation has been shown to be an intrinsic property of many proteins including proteins not involved in amyloid diseases. The most common types of protein aggregates are amyloid fibrils and amorphous ...
Influence of soluble factors secreted by different types of fibroblasts on differentiation of human embryonic stem cells into retinal pigment epithelial cells.
(2011)
Pro gradu -tutkielma
Pro gradu -tutkielma
Tutkielman tausta ja tavoitteet: Ihmisen alkion kantasolujen ainutlaatuisten ominaisuuksien ansiosta niitä voidaan hyödyntää monien sairauksien hoidossa. Esimerkiksi verkkokalvon pigmenttiepiteelisolujen rappeutumiseen ...
Towards a Macrolide Biosensor: Mutation and Production of MphR(E) Repressor Protein
(2011)
Pro gradu -tutkielma
Pro gradu -tutkielma
Background and aims: Among other antibiotics macrolides have been used in a large scale for decades which leads into an increase of antibiotics in food, feed and environment and results in antibiotic resistance in ...