Haku
Viitteet 11-20 / 103
Polymorphisms of the Antioxidative Enzyme Paraoxonase-1 in the Development of Atherosclerosis
(Tampere University Press, 2003)
Väitöskirja
Väitöskirja
Valtimonkovettumataudilla eli ateroskleroosilla tarkoitetaan tilaa, jossa valtimoiden seinämiin kertyy rasvaa ja ne kovettuvat iän myötä. Ateroskleroosin yleisimmät kliiniset ilmenemismuodot, sepelvaltimotauti ja ...
Cytosolic SH3-interactions of ADAM12-disintegrin-metalloprotease
(2007)
Pro gradu -tutkielma
Pro gradu -tutkielma
Background: ADAM proteins (a disintegrin and metalloprotease) are membrane proteins that consist of several functional domains. ADAM proteins are able to mediate cell adhesion through their disintegrin domain and selective ...
Small-molecules as regulatory T cell modulators: A pilot screen
(2008)
Pro gradu -tutkielma
Pro gradu -tutkielma
Backround and aims: Regulatory T cells are widely recognized as key players of immune control and have been shown to function in many immune related diseases. This has lead to intensive research efforts and high hopes for ...
Expression of interleukin-10 family cytokines in rheumatoid arthritis
(2007)
Pro gradu -tutkielma
Pro gradu -tutkielma
Background and aims: Interleukin-10 (IL-10) is an anti-inflammatory cytokine, and its expression is increased in rheumatoid arthritis (RA). A number of novel cytokines have been found recently, which have been designated ...
Expression of Carbonic Anhydrases IX and XII in Embryonic and Adult Mouse Tissues
(2006)
Pro gradu -tutkielma
Pro gradu -tutkielma
Background and aims: Of the thirteen active carbonic anhydrases, CA IX and XII have been linked to carcinogenesis. It has been suggested that these membrane-bound CAs participate in cancer cell invasion. Since active cell ...
Characterization of repression capability of Sin3-associated protein 30-like and its alternatively spliced isoforms
(2008)
Pro gradu -tutkielma
Pro gradu -tutkielma
Background and Aims: Within the nucleus of eukaryotic cell, DNA is packaged with histone proteins to from nucleosomes that arrange further to form higher-order packaged structures. This three dimensional structure forms a ...
Tenogenic differentiation of human adipose stem cells on braided polylactide scaffold
(2013)
Pro gradu -tutkielma
Pro gradu -tutkielma
Hyperuricemia and the renin-angiotensin-aldosterone system in experimental renal insufficiency
(2008)
Pro gradu -tutkielma
Pro gradu -tutkielma
Background and Aims – Hyperuricemia is associated with renal insufficiency and may predispose to Na+ retention and hypertension. Whether hyperuricemia plays a causal role in the pathogenesis of cardiovascular disease remains ...
Effects of the androgen receptor overexpression in prostate cancer
(2007)
Pro gradu -tutkielma
Pro gradu -tutkielma
Background and aims: Prostate cancer is the leading cancer type in Finnish men. In about 30% of patients, the proceeding into a fatal hormone independent state involves the amplification and overexpression of the androgen ...
Neural stem cell transplantation in mouse model of juvenile neuronal ceroid-lipofuscinosis
(2008)
Pro gradu -tutkielma
Pro gradu -tutkielma
Background and Aims: This thesis investigates the suitability of neural stem cell transplantation in a mouse model of juvenile neuronal ceroid-lipofuscinosis (JNCL). JNCL is a childhood neurodegenerative disease leading ...