Haku
Viitteet 1-8 / 8
Working towards a 3D hepatic model: Induced pluripotent stem cell-derived hepatocyte-like cells, their differentiation and viability in 3D hydrogel cultures and on microfluidic chips
(2020)
Pro gradu -tutkielma
Pro gradu -tutkielma
Background and objectives of the study: This master’s thesis consists of three parts involving induced pluripotent stem cell-derived hepatocyte-like cells (iPSC-HLCs). iPSC-HLCs provide an alternative cell model for primary ...
Whole blood virome in rheumatoid arthritis
(2020)
Pro gradu -tutkielma
Pro gradu -tutkielma
Recent research has shown that human body is host to billions of microbes, including viruses. Set of all viruses found in specific environment, such as in single human organ, is called a virome. In addition, certain viruses ...
Effect of A-type lamins on nucleus morphology in epithelial cells: A-tyypin lamiinien vaikutus tuman muotoon epiteelisoluissa
(2020)
Pro gradu -tutkielma
Pro gradu -tutkielma
Background and aims: Mechanical forces are known to play essential roles in tissue ho-meostasis and development. Recently, it has been established that physical forces can travel from the extracellular matrix through the ...
The effect of alternative respiratory pathways on cell metabolism
(2020)
Pro gradu -tutkielma
Pro gradu -tutkielma
Single-cell RNA-Seq deconvolution of glioblastoma bulk transcriptomics
(2020)
Pro gradu -tutkielma
Pro gradu -tutkielma
Background and aims of study: Glioblastoma multiforme is the most malignant primary brain cancer. Improvement in immunotherapies has shown positive signs in cancer treatment, and brain's immune microenvironment is a promising ...
Mycobacterium marinum biofilm: a tool to study and target persistent tuberculosis
(2020)
Pro gradu -tutkielma
Pro gradu -tutkielma
Tuberculosis remains a widespread and deadly infectious disease, especially in the developing world. Despite the availability of effective antibiotics, treatment of the infection is challenging due to the extreme persistence ...
Epigenetic mechanisms translating cellular energy homeostasis to differentiation of the intestinal epithelium
(2020)
Pro gradu -tutkielma
Pro gradu -tutkielma
Background and aims: The small intestine has many important functions, which constitute to the welfare of the whole organism. These vital functions are mediated by community of intestinal epithelial cells. However, the ...