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Establishment of New Micro-Computed Tomography Methodologies : The use of Histology as a Complementary Tool
(2020)
Pro gradu -tutkielma
Pro gradu -tutkielma
Introduction: During the last decade, the study of biological structures in 3D has gained great importance due to its potential benefits in medical diagnosis and research. Micro-computed tomography (µCT) makes this approach ...
Analysis of Commercial Electronic Quality Management Systems for Medical Devices
(2022)
Diplomityö
Diplomityö
Medical Devices play an essential role in delivering healthcare in home and hospital settings. Medical Devices are regulated in Europe and the United States to ensure effective and safe usage of devices and prevent problems ...
Smart Shirt and Carpet for Monitoring Eye-Contact in Autism Research
(2021)
Diplomityö
Diplomityö
Differentially methylated topologically associating domains in brain tumors
(2021)
Diplomityö
Diplomityö
In recent years, cancer has become one of the main causes of human death all over the world. Cancer is a generation of unhealthy cells that neither grow nor operate normally. Central nervous system (CNS) tumor is a creation ...
Medical Device Development from R&D to Commercialization: Case 1 - Mental Pin and Case 2 - Unsomia
(2021)
Pro gradu -tutkielma
Pro gradu -tutkielma
Objective: To provide a practical guidance for medical device development from Lab to market in early-stage projects by comparing the results of two real-life examples and highlighting the lessons learned. And to evaluate ...
Characterization of Photo-Crosslinking ECM-Mimetic Gallol Modified Hyaluronic Acid-Protein Composite Hydrogels
(2021)
Diplomityö
Diplomityö
The need for multifunctional advanced hydrogel materials for biomedical research and biomedicine has never been greater to find better alternatives to animal modelling and to make more physiologically relevant in vitro ...
Correspondence analysis between remifentanil concentrations and monitored physiological measures in children.
(2022)
Diplomityö
Diplomityö
Background & Objective: There is scarce research done towards the development of target-controlled infusion models (TCI) for the opioid analgesic drug known as remifentanil in anaesthesia. TCI models reduce the incidence ...
Characterizing oxygen transport in hydrogel on a 3D microfluidic chip
(2022)
Diplomityö
Diplomityö
OOC models are microfluidic systems, designed to mimic the physiological processes of specific human organs. On a cellular level, sufficient O2 supply is crucial for the viability of cells in cell cultures. In culture ...
Spatial chromatin accessibility : a computational method for single cell ATAC-seq and spatial transcriptomics data integration
(2023)
Diplomityö
Diplomityö
Cell fate is largely determined by the intricate interplay of chromatin compression and gene expression regulation. Expression can be suppressed by tightly packing the chromatin or enhanced by unwinding the DNA strand in ...