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The role of carbonic anhydrase VI in bitter taste perception: evidence from the Car6 -/- mouse model
(2014)
- article
Background
Carbonic anhydrase VI (CA VI) is a secretory isozyme of the α-CA gene family. It is highly expressed in the salivary and mammary glands and secreted into saliva and milk. Although CA VI was first described ...
Mapping of the chromosomal amplification 1p21-22 in bladder cancer
(2014)
- article
Background
The aim of the study was to characterize a recurrent amplification at chromosomal region 1p21-22 in bladder cancer.
Methods
ArrayCGH (aCGH) was performed to identify DNA copy number variations in 7 clinical ...
Kantasoluista sykkiviä sydänsoluja
(2014)
- article
Täsmädiagnostiikkaa, yksilöllistä hoidon optimointia ja räätälöityjä soluhoitoja
Sydäninfarkti aiheuttaa sydämen arpeutumisen ja toimintakyvyn menetyksen, koska sydän ei pysty itse korjaamaan vahingoittunutta aluetta. ...
Silmän kantasoluhoidot
(2014)
- article
Bioinformatic analysis of beta carbonic anhydrase sequences from protozoans and metazoans
(2014)
- article
Background
Despite the high prevalence of parasitic infections, and their impact on global health and economy, the number of drugs available to treat them is extremely limited. As a result, the potential consequences ...
Assessing interactions of two loci (rs4242382 and rs10486567) in familial prostate cancer : statistical evaluation of epistasis
(2014)
- article
Understanding the impact of multiple genetic variants and their interactions on the disease penetrance of familial multiple prostate cancer is very relevant to the overall understanding of carcinogenesis. We assessed the ...
Video image-based analysis of single human induced pluripotent stem cell derived cardiomyocyte beating dynamics using digital image correlation
(2014)
- article
Background
The functionality of a cardiomyocyte is primarily measured by analyzing the electrophysiological properties of the cell. The analysis of the beating behavior of single cardiomyocytes, especially ones derived ...
Beta carbonic anhydrases: novel targets for pesticides and anti-parasitic agents in agriculture and livestock husbandry
(2014)
- article
Abstract
BACKGROUND:
The genomes of many insect and parasite species contain beta carbonic anhydrase (β-CA) protein coding sequences. The lack of β-CA proteins in mammals makes them interesting target proteins for ...