Haku
Viitteet 1-10 / 20
Characterization of in vitro outer blood retinal barrier model
(2015)
Pro gradu -tutkielma
Pro gradu -tutkielma
Background and aims: The human eye has anatomically closed structure, due to the blood retinal barrier (BRB) which is protecting the photoreceptor cells. It comprises of three layers: retinal pigment epithelial cells ...
Functional Characterization of the Kinase and Pseudokinase Domains in the Janus Tyrosine Kinase (JAK) 2
(Tampere University Press, 2014)
Artikkeliväitöskirja
Artikkeliväitöskirja
Hematopoieesin eli verenmuodostuksen aikana liukoiset sytokiinimolekyylit säätelevät tarkasti solujen kasvua ja erilaistumista. Sytokiinit aktivoivat JAK/STAT-signaalinvälitysreitin, jolla on merkittävä rooli verisolujen ...
Effects of uniaxial strain in hypertrophic cardiomyopathy -patient specific human induced pluripotent stem cell -derived cardiomyocytes
(2014)
Pro gradu -tutkielma
Pro gradu -tutkielma
Background and aims: Hypertrophic cardiomyopathy (HCM) is genetically inherited autosomal-dominant disease with significant genotypic and phenotypic heterogeneity. HCM is one of the most common inherited cardiovascular ...
Evaluation of the pluripotency of human induced pluripotent stem cells (hiPSCs) reprogrammed with integrative and non-integrative protocols and their differentiation into cardiomyocytes
(2014)
Pro gradu -tutkielma
Pro gradu -tutkielma
Research background and aims: The purpose of this research was to evaluate the pluripotency of integrative retro and non-integrative Sendai virally generated human induced pluripotent stem cells (hiPSCs) and their cardiac ...
Characterisation of dopamine neurons of the murine ventral tegmental area in primary culture and acute dissociations
(2014)
Pro gradu -tutkielma
Pro gradu -tutkielma
Dopamine (DA) neurons play pivotal roles in the regulation of motor and endocrine functions, as well as affective and cognitive behaviours. The degeneration and dysregulation of these neurons has been linked to the ...
Production and characterization of human carbonic anhydrase IX in insect cells
(2014)
Pro gradu -tutkielma
Pro gradu -tutkielma
Carbonic anhydrase IX (CA IX) is a cell surface enzyme, which catalyzes CO2 hydration. It has a function to maintain favorable pH conditions for cancer cell growth and survival. Expression of CA IX is a marker of hypoxia, ...
Towards alkane production in Acinetobacter baylyi
(2014)
Pro gradu -tutkielma
Pro gradu -tutkielma