Haku
Viitteet 1-10 / 30
Simulation of IP3 receptor function in cerebellar Purkinje cell dendritic spine: Importance of stochasticity
(2007)
Pro gradu -tutkielma
Pro gradu -tutkielma
Background and aims: This thesis investigates calcium dynamics in cerebellar Purkinje cells. A special emphasis is put on the Purkinje cells dendritic spines where most of the synapses are formed. Transient rises in cytosolic ...
Distribution of Novel Iron Regulatory Protein Hemojuvelin in Murine Tissues
(2005)
Pro gradu -tutkielma
Pro gradu -tutkielma
Hakutermit:
iron, hemochromatosis, hemojuvelin, in situ hybridization, immunohistochemistry, localization
Backgroung and Aims: Juvenile hemochromatosis is an early-onset iron overload disease that leads to severe organ ...
The 9p13.3 amplicon in prostate cancer
(2007)
Pro gradu -tutkielma
Pro gradu -tutkielma
Tutkimuksen tausta ja tavoitteet: Eturauhassyöpä on miesten yleisin syöpä Suomessa. Eturauhassyövän molekulaariset mekanismit ovat vielä epäselviä ja vain muutama todellinen kohdegeeni on löydetty. Tämän tutkimuksen ...
A search of proteins that interact with Sin3A-associated proteins 30 and 30-like
(2006)
Pro gradu -tutkielma
Pro gradu -tutkielma
Expression of membrane-bound carbonic anhydrase isozyme XII in mouse and rat tissues
(2006)
Pro gradu -tutkielma
Pro gradu -tutkielma
Background and aims: Carbonic anhydrase XII (CA XII) is a membrane-bound isozyme expressed in some normal human tissues, upregulated in some cancers, and is showed to be a hypoxia-inducible gene product. The expression of ...
Polymorphisms of the Antioxidative Enzyme Paraoxonase-1 in the Development of Atherosclerosis
(Tampere University Press, 2003)
Väitöskirja
Väitöskirja
Valtimonkovettumataudilla eli ateroskleroosilla tarkoitetaan tilaa, jossa valtimoiden seinämiin kertyy rasvaa ja ne kovettuvat iän myötä. Ateroskleroosin yleisimmät kliiniset ilmenemismuodot, sepelvaltimotauti ja ...
Cytosolic SH3-interactions of ADAM12-disintegrin-metalloprotease
(2007)
Pro gradu -tutkielma
Pro gradu -tutkielma
Background: ADAM proteins (a disintegrin and metalloprotease) are membrane proteins that consist of several functional domains. ADAM proteins are able to mediate cell adhesion through their disintegrin domain and selective ...
Small-molecules as regulatory T cell modulators: A pilot screen
(2008)
Pro gradu -tutkielma
Pro gradu -tutkielma
Backround and aims: Regulatory T cells are widely recognized as key players of immune control and have been shown to function in many immune related diseases. This has lead to intensive research efforts and high hopes for ...
Expression of interleukin-10 family cytokines in rheumatoid arthritis
(2007)
Pro gradu -tutkielma
Pro gradu -tutkielma
Background and aims: Interleukin-10 (IL-10) is an anti-inflammatory cytokine, and its expression is increased in rheumatoid arthritis (RA). A number of novel cytokines have been found recently, which have been designated ...
Expression of Carbonic Anhydrases IX and XII in Embryonic and Adult Mouse Tissues
(2006)
Pro gradu -tutkielma
Pro gradu -tutkielma
Background and aims: Of the thirteen active carbonic anhydrases, CA IX and XII have been linked to carcinogenesis. It has been suggested that these membrane-bound CAs participate in cancer cell invasion. Since active cell ...