Haku
Viitteet 1-10 / 23
Feature selection for classification of single amino acid variations
(2012)
Pro gradu -tutkielma
Pro gradu -tutkielma
Genetic variations that lead to changes in amino acid sequences have the ability to cause structural and functional changes of proteins. All such variations do not show phenotypic effects, so it is important to have ...
Aggregation prediction; A bioinformatics method for studying the effects of missense variations on pathogenicity
(2012)
Pro gradu -tutkielma
Pro gradu -tutkielma
Background and Aims: Aggregation has been shown to be an intrinsic property of many proteins including proteins not involved in amyloid diseases. The most common types of protein aggregates are amyloid fibrils and amorphous ...
Evaluation of the cell-free mitochondrial DNA quantity in plasma as an aging biomarker candidate
(2012)
Pro gradu -tutkielma
Pro gradu -tutkielma
Background and aims: Individuals of the same species may have large variations in their ageing rates, especially notable at higher ages. Therefore, it is proposed that chronological age is not suitable for measuring ones ...
Development of a serotype-specific detection method for the diabetogenic coxsackievirus B1
(2012)
Pro gradu -tutkielma
Pro gradu -tutkielma
Analysis of evolutionary pressure and pathogenicity of missense variations
(2012)
Pro gradu -tutkielma
Pro gradu -tutkielma
Background and aims: Gene and protein sequences are subject to variation upon reproduction where favorable alleles are expressed in further generations by positive selection and bad alleles are being eliminated by means ...
Pentraxin -Carbonic anhydrase CA VI: A novel multidomain protein
(2012)
Pro gradu -tutkielma
Pro gradu -tutkielma
Tutkimuksen tausta ja tavoitteet: Hiilihappoanhydraasi- proteiinit (carbonic anhydrases, CAs) toimivat kudoksien ja nesteiden pH:n säätelyssä katalysoiden CO2 + H2O HCO3− + H+ reaktiota. Hiilihappoanhydraasit ovat ...
Setting up Methods for the Study of Intracellular Mechanotransduction
(2012)
Pro gradu -tutkielma
Pro gradu -tutkielma
Fokaaliadheesiot (FA) ovat suuria proteiinikomplekseja, joiden avulla solut tarttuvat ympäristönsä solunulkoiseen matriksiin liittämällä sen mekaanisesti solunsisäiseen tukirankaansa. FA:t ovat mekanosensorisia rakenteita, ...
Fluorescent labeling of human embryonic stem cell -derived neurons and characterization of their network connection development
(2012)
Pro gradu -tutkielma
Pro gradu -tutkielma
Cell transplantation therapy is an alternative treatment for defects in tissues with poor regeneration and lack of efficient treatments. One of such tissues is the central nervous system tissue. However, cell transplantation ...
Influence of pluripotent stem cell culture conditions on cardiac differentiation
(2012)
Pro gradu -tutkielma
Pro gradu -tutkielma
Tutkimuksen tausta ja tavoitteet: Soluviljelyssä tavoitteena on pitää kantasolut erilaistumattomina. Kantasolujen tulisi kasvaa yhtenäisen näköisinä ja pyöreä-reunaisina kolonioina ja niiden spontaani erilaistuminen tulisi ...