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Sodium channels enable fast electrical signaling and regulate phagocytosis in the retinal pigment epithelium
(2019)
- article
Background: Voltage-gated sodium (Nav) channels have traditionally been considered a trademark of excitable cells. However, recent studies have shown the presence of Nav channels in several non-excitable cells, such as ...
Activity Level and Body Mass Index as Predictors of Physical Workload During Working Career
(2019-12)
- article
The increasing prevalence of inactivity and obesity, along with aging, has implications on work capacity of labor force. This study reports the relationships between activity level and BMI by age with objectively measured ...
Unique Features of Network Bursts Emerge From the Complex Interplay of Excitatory and Inhibitory Receptors in Rat Neocortical Networks
(2019-09-06)
- article
Spontaneous network activity plays a fundamental role in the formation of functional networks during early development. The landmark of this activity is the recurrent emergence of intensive time-limited network bursts (NBs) ...
Effect of melt-derived bioactive glass particles on the properties of chitosan scaffolds
(2019)
- article
This study reports on the processing of three-dimensional (3D) chitosan/bioactive glass composite scaffolds. On the one hand, chitosan, as a natural polymer, has suitable properties for tissue engineering applications but ...
Mechanical characterization of pore-graded bioactive glass scaffolds produced by robocasting
(2019)
- article
Since the discovery of 45S5 Bioglass® by Larry Hench, bioactive glasses have been widely studied as bone substitute materials and, in more recent years, have also shown great promise for producing three-dimensional scaffolds. ...
The national SotePeda 24/7 project develops future professional competencies for the digital health and social care sector in Finland
(2019-05-06)
- conferenceObject
The SotePeda 24/7 project, financed by the Finnish Ministry of Education and Culture, aims at increasing competencies in developing digital services in the health and social care sector, and to create digital pedagogical ...
Data-driven multiscale modeling reveals the role of metabolic coupling for the spatio-temporal growth dynamics of yeast colonies
(2019-12-19)
- article
Background: Multicellular entities like mammalian tissues or microbial biofilms typically exhibit complex spatial arrangements that are adapted to their specific functions or environments. These structures result from ...
Estimating RNA numbers in single cells by RNA fluorescent tagging and flow cytometry
(2019)
- article
Estimating the statistics of single-cell RNA numbers has become a key source of information on gene expression dynamics. One of the most informative methods of in vivo single-RNA detection is MS2d-GFP tagging. So far, it ...
Hyaluronan derived nanoparticle for simvastatin delivery: evaluation of simvastatin induced myotoxicity in tissue engineered skeletal muscle
(2019-11-01)
- article
Statins are currently the most prescribed hypercholesterolemia-lowering drugs worldwide, with estimated usage approaching one-sixth of the population. However, statins are known to cause pleiotropic skeletal myopathies in ...
Core-clad phosphate glass fibers for biosensing
(2019-03)
- article
Recently, a phosphate glass with composition 20 CaO-20 SrO-10 Na2O-50 P2O5 (mol%) was found to have good potential as a biomaterial and to possess thermal properties suitable for fiber drawing. This study opened the path ...