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Pot-economy autooxidative condensation of 2-Aryl-2-lithio-1,3-dithianes
The autoxidative condensation of 2-aryl-2-lithio-1,3-dithianes is here reported. Treatment of 2-aryl-1,3-dithianes with n-BuLi in the absence of any electrophile leads to condensation of three molecules of 1,3-dithianes ...
How Cardiolipin Peroxidation Alters the Properties of the Inner Mitochondrial Membrane?
Cardiolipins have multiple vital functions within biological cell membranes, most notably in the energy metabolism associated with the inner mitochondrial membrane. Considering their essential role, peroxidation of ...
The effect of light sensitizer localization on the stability of indocyanine green liposomes
Light triggered drug delivery systems offer attractive possibilities for sophisticated therapy, providing both temporal and spatial control of drug release. We have developed light triggered liposomes with clinically ...
Crystallization Kinetics of an Amorphous Pharmaceutical Compound Using Fluorescence-Lifetime-Imaging Microscopy
Pharmaceutical scientists are increasingly interested in amorphous drug formulations especially because of their higher dissolution rates. Consequently, the thorough characterization and analysis of these formulations are ...
Quantification of bio-anode capacitance in bioelectrochemical systems using Electrochemical Impedance Spectroscopy
Understanding the electrochemical properties of bio-anodes is essential to improve performance of bioelectrochemical systems. Electrochemical Impedance Spectroscopy (EIS) is often used to study these properties in detail. ...
Regulation of asymmetries in the kinetics and protein numbers of bacterial gene expression
Genetic circuits change the status quo of cellular processes when their protein numbers cross thresholds. We investigate the regulation of RNA and protein threshold crossing propensities in Escherichia coli. From in vivo ...
An Integrated Hardware/Software Design Methodology for Signal Processing Systems
This paper presents a new methodology for design and implementation of signal processing systems on system-on-chip (SoC) platforms. The methodology is centered on the use of lightweight application programming interfaces ...
Spatial solitons to mold random lasers in nematic liquid crystals [Invited]
Dye-doped nematic liquid crystals support random lasing under optical pumping, as well as reorientational optical spatial solitons acting as all-optical waveguides. By synergistically combining these two responses in a ...
Impact of Variable RNA-Sequencing Depth on Gene Expression Signatures and Target Compound Robustness : Case Study Examining Brain Tumor (Glioma) Disease Progression
Purpose: Gene expression profiling can uncover biologic mechanisms underlying disease and is important in drug development. RNA sequencing (RNA-seq) is routinely used to assess gene expression, but costs remain high. Sample ...
Characterization of flame coated nanoparticle surfaces with antibacterial properties and the heat-induced embedding in thermoplastic-coated paper
Silver nanoparticles deposited on surfaces can provide an antibacterial effect with potential uses in, for example, healthcare settings. However, release of nanoparticles and their potential exposure to the environment is ...