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Associations between Engagement with the BitHabit Digital Lifestyle Intervention and Changes in Type 2 Diabetes Risk Factors
(IOS Press, 2023-05-18)
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Type 2 diabetes (T2D) can be prevented or delayed through a healthy lifestyle. Digital behavior change interventions (DBCIs) may offer cost-effective and scalable means to support lifestyle changes. This study investigated ...
Detection and outcome of endocervical atypia in cytology in primary HPV screening programme
(2021-12)
- article
Most endocervical adenocarcinomas (EAC) are associated with high-risk HPV (hrHPV) infection, with HPV genotypes 16, 18 and 45 accounting for >90% of the cases. Among endocervical glandular lesions, screening with hrHPV ...
Prevalence and prognostic significance of depressive symptoms in a geriatric post-hip fracture assessment
(2022)
- article
Objectives: To investigate the prevalence and prognostic significance of post-hip fracture depressive symptoms. Methods: A naturalistic clinical cohort study. Data were collected on admission to hospital, geriatric assessment ...
Combined Longitudinal Clinical and Autopsy Phenomic Assessment in Lethal Metastatic Prostate Cancer : Recommendations for Advancing Precision Medicine
(2021-08)
- article
Background: Systematic identification of data essential for outcome prediction in metastatic prostate cancer (mPC) would accelerate development of precision oncology. Objective: To identify novel phenotypes and features ...
Presence of high-risk HLA genotype is the most important individual risk factor for coeliac disease among at-risk relatives
(2021)
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Background: Family screening has been advocated as a means to reduce the major underdiagnosis of coeliac disease. However, the precise risk of the disease in relatives and the impact of patient- and relative-related ...
Reliability of the freehand region-of-interest method in quantitative cerebral diffusion tensor imaging
(2021)
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Background: Diffusion tensor imaging (DTI) is a magnetic resonance imaging (MRI) technique used for evaluating changes in the white matter in brain parenchyma. The reliability of quantitative DTI analysis is influenced by ...
Are There Limits in Explainability of Prognostic Biomarkers? : Scrutinizing Biological Utility of Established Signatures
(2021-10-12)
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Prognostic biomarkers can have an important role in the clinical practice because they allow stratification of patients in terms of predicting the outcome of a disorder. Obstacles for developing such markers include lack ...
Modulation of the food microbiome by apple fruit processing
(2022)
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During the early life, introduction to external exposures such as consumption of solid foods contribute to the development of the gut microbiota. Among solid foods, fruit and vegetables are normally consumed during early ...
Circulating cell-free DNA in health and disease : the relationship to health behaviours, ageing phenotypes and metabolomics
(2023)
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Circulating cell-free DNA (cf-DNA) has emerged as a promising biomarker of ageing, tissue damage and cellular stress. However, less is known about health behaviours, ageing phenotypes and metabolic processes that lead to ...