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Edin Expression in the Fat Body Is Required in the Defense Against Parasitic Wasps in Drosophila melanogaster
(2015)
- article
The cellular immune response against parasitoid wasps in Drosophila involves the activation, mobilization, proliferation and differentiation of different blood cell types. Here, we have assessed the role of Edin (elevated ...
Computational Model of Ca2+ Wave Propagation in Human Retinal Pigment Epithelial ARPE-19 Cells
(2015)
- article
Abstract
Objective
Computational models of calcium (Ca2+) signaling have been constructed for several cell types. There are, however, no such models for retinal pigment epithelium (RPE). Our aim was to construct a Ca2+ ...
Length of prostate biopsies is not necessarily compromised by pooling multiple cores in one paraffin block: an observational study
(2015)
- article
Background
Individually submitted prostatic needle biopsies are recommended by most guidelines because of their potential advantage in terms of core quality. However, unspecified bilateral biopsies are commonly submitted ...
A study of genes encoding cytokines (IL6, IL10, TNF), cytokine receptors (IL6R, IL6ST), and glucocorticoid receptor (NR3C1) and susceptibility to bronchopulmonary dysplasia
(2014)
- article
Background
Bronchopulmonary dysplasia (BPD) is a common chronic lung disease associated with very preterm birth. The major risk factors include lung inflammation and lung immaturity. In addition, genetic factors play ...
The evolution and function of the minimal mitochondrial DNA replisome
(2014)
Pro gradu -tutkielma
Pro gradu -tutkielma
Epithelium percentage estimation facilitates epithelial quantitative protein measurement in tissue specimens
(2013)
- article
Background
The rapid advancement of high-throughput tools for quantitative measurement of proteins has demonstrated the potential for the identification of proteins associated with cancer. However, the quantitative ...
POMO - Plotting Omics analysis results for Multiple Organisms
(2013)
- article
Systems biology experiments studying different topics and organisms produce thousands of data values across different types of genomic data. Further, data mining analyses are yielding ranked and heterogeneous results and ...
Ageing-associated changes in the human DNA methylome: genomic locations and effects on gene expression
(2015)
- article
Background
Changes in DNA methylation are among the mechanisms contributing to the ageing process. We sought to identify ageing-associated DNA methylation changes at single-CpG-site resolution in blood leukocytes and ...
Background and specific contrast enhancements for imaging biological samples with micro-computational tomography
(2014)
Pro gradu -tutkielma
Pro gradu -tutkielma