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Early glucose metabolism in children at risk for type 1 diabetes based on islet autoantibodies compared to low-risk control groups
(2022-09-12)
- article
Background: Anatomic variation or early differences in glucose metabolism have been linked to the development of type 1 diabetes. We aimed to describe early glucose metabolism based on HbA1c, oral glucose tolerance test ...
Maternal childbirth experience and time of delivery : A retrospective 7-year cohort study of 105 847 parturients in Finland
(2021-06-16)
- article
Objectives To explore how the time of delivery influences childbirth experience. Design A retrospective cohort study. Setting Childbirth in the four Helsinki and Uusimaa Hospital District hospitals, Finland, from 2012 to ...
Associations between Gut Microbiota and Intestinal Inflammation, Permeability and Damage in Young Malawian Children
(2022-02)
- article
BACKGROUND: Environmental enteric dysfunction (EED) is common in low- and middle-income countries and associated with childhood undernutrition. The composition of gut microbiota has been implicated in the pathogenesis of ...
Change in medical practice over time? : A register based study of regional trends in hysterectomy in Finland in 2001–2018
(2021-06)
- article
Background: A persistent research finding in Finland and elsewhere has been variation in medical practices both between and within countries. Variation seems to exist especially if medical decision making involves discretion ...
Maternal meal irregularities during pregnancy and lifestyle correlates
(2022)
- article
Meal regularity can influence metabolic health. However, habits of skipping and delaying meals are rarely studied among pregnant women. This study examined the incidence of maternal meal skipping and meal delaying, and ...
Breastfeeding and circulating immunological markers during the first 3 years of life : the DIABIMMUNE study
(2022)
- article
Aims/hypothesis: Our aim was to study the association between duration of breastfeeding and circulating immunological markers during the first 3 years of life in children with HLA-conferred susceptibility to type 1 diabetes. ...
25(OH)D Levels in Infancy Is Associated With Celiac Disease Autoimmunity in At-Risk Children : A Case–Control Study
(2021-08-11)
- article
Objectives: An observed variation in the risk of celiac disease, according to the season of birth, suggests that vitamin D may affect the development of the disease. The aim of this study was to investigate if vitamin D ...
Impact of diagnostic delay to the clinical presentation and associated factors in pediatric inflammatory bowel disease : a retrospective study
(2021-10)
- article
Background: Undelayed diagnosis is thought to be a major determinant for good prognosis in pediatric inflammatory bowel disease (PIBD). However, factors predicting diagnostic delay and the consequences of this remain poorly ...
Provision of small-quantity lipid-based nutrient supplements does not improve intestinal health among rural Malawian children
(2022)
- article
Lipid-based nutrient supplements (LNS) have been found to improve child growth and reduce child mortality. However, the mechanistic pathways for these improvements warrant exploration. One potential pathway is linked to ...
Interleukin 1 receptor-like 1 rs13408661/13431828 polymorphism is associated with persistent post-bronchiolitis asthma at school age
(2022-03)
- article
Aim: Interleukin (IL) 1 receptor-like 1, encoded by the IL1RL1 gene, is a receptor for IL-33. In European birth cohorts, IL1RL1 rs102082293, rs10204137 (rs4988955), rs13424006 and rs13431828 (rs13048661) variations were ...