Trepo - Selaus Tutkinto-ohjelman ja opintosuunnan mukaan
Viitteet 1-20 / 58
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A new method for long-term culturing of intestinal biopsies derived from Celiac Disease patients using mice as carriers
(2016)
Pro gradu -tutkielmaCeliac disease (CD) is a complex disorder with no bona fide animal model that would exhibit all the features of the disorder. The small-intestinal mucosal biopsies commonly used to study the disease present a limiting ... -
A pipeline to optimize metabolic pathways in the synthetically regulated Saccharomyces cerevisiae using tryptophan pathway as an example
(2016)
Pro gradu -tutkielmaBackground and aims: Cell factories are currently used to produce biochemicals for nutrition, pharma, medical, and energy industries with a high future potential and interest among these and other industries. General ... -
Activation of Intracellular Signalling Pathways in Adipose Stem Cell- mediated Immunosuppression
(2016)
Pro gradu -tutkielmaBackground and aims: Adipose tissue is a source of multipotent adipose stromal/stem cells (ASCs). ASCs have excellent proliferation and multilineage differentiation capacity, low immunogenicity and promising immunosuppressive ... -
Adipose stem cells and structural composites in the engineering of vascularized bone tissue
(2013)
Pro gradu -tutkielma -
Allergic asthma and rhinovirus infections in a birth cohort study in Finland and Estonia
(2016)
Pro gradu -tutkielma -
Biochemical and biophysical characterization of saliva- and milk human carbonic anhydrase VI : maidon ja syljen hiilihappoanhydraasi VI:n biokemiallinen ja biofysikaalinen karakterisointi
(2019)
Pro gradu -tutkielmaBackground and aims of study: Carbonic anhydrase VI, CA VI, belongs to carbonic anhydrase isoenzymes that is known to secrete from serous acinar cells in the salivary glands and mammary gland to saliva and milk, respectively. ... -
Catalytic mechanism for reduction of bicarbonate in the active site of formate dehydrogenase
(2016)
Pro gradu -tutkielmaFormate dehydrogenases (FDHs) are a set of mostly homodimeric oxidoreductases that catalyze the oxidation of formate to carbon dioxide with the concurrent reduction of NAD+ to NADH. These enzymes are common to methylotropic ... -
Characterization of oncogenic role of ROR1 and PTK7 in B-ALL
(2018)
Pro gradu -tutkielmaBackground and aims: Pseudokinases are members of the protein kinase superfamily that have mutations in their canonical motifs required for proper catalytic activity. Many pseudokinases are involved in human diseases, ... -
Co-culture of corneal epithelial cells and adipose stem cells - towards the use of hydrogels in ocular surface reconstruction
(2016)
Pro gradu -tutkielmaObjectives: In a tissue engineering field, co-culture techniques of different kind have been widely researched in recent years to form physiologically relevant cell structures for different tissue reconstructions. The ... -
Comparison of snv genotyping sensitivity of next-generation sequencing with illumina's miseq and quantitative real-time pcr with fluidigm's biomark hd
(2016)
Pro gradu -tutkielmaYhden nukleotidin variantti-genotyypitys (SNV-genotyypitys) on menetelmä, jota voisi soveltaa rutiininomaisesti syöpä-diagnostiikassa. Sitä ei käytetä, koska teknologiat joita menetelmä hyödyntää ovat suhteellisen uusia. ... -
Computational analysis of glioblastoma immune microenvironment
(2018)
Pro gradu -tutkielma -
Construction of knockout Mycobacterium marinum mutants to study reactivation of mycobacteria
(2018)
Pro gradu -tutkielma -
Coxsackievirus B1 mutation analysis
(2018)
Pro gradu -tutkielma -
Defining the mechanism of action of multi-walled carbon nanotubes on immune cells in vitro
(2019)
Pro gradu -tutkielmaEngineered nanomaterials (ENM) are a rapidly expanding class of chemicals with applications spanning from cosmetics to food, and from industrial applications to pharmaceuticals. Some ENM are already known to be harmful to ... -
Determination of source and quantity of DNA in spent embryo culture medium
(2017)
Pro gradu -tutkielmaTiivistelmä: Tutkimuksen tausta ja tavoitteet: Alkiodiagnostiikka hedelmöityshoidoissa on enenemässä määrin tarpeellinen erityisesti ensisynnyttäjien keski-iän noustessa, jolloin alkioiden kromosomipoikkeavuudet lisääntyvät ... -
Development of antigen-decorated norovirus-like particles for vaccine applications
(2018)
Pro gradu -tutkielmaDue to limitations in current influenza vaccines, an innumerable number of people are taken to bed and over 200,000 lives are lost yearly to seasonal influenza. This thesis work aimed to create a prototype vaccine that ... -
Development of MP-SPR biosensor analysis methology
(2017)
Pro gradu -tutkielmaOptical biosensors have gained high regard in the field of drug industry and clinical diagnostics owing to the high specificity of biological recognition elements as well as to the non-invasiveness of optical detection ... -
Differentiation Potential of the Human Adipose Stem Cells in Response to Regulation of ROCK, FAK and MEK-ERK Signaling Pathways
(2015)
Pro gradu -tutkielmaBackground and aims: Adipose stem cells (ASCs), obtained from adipose tissue, are a promising cell source for bone tissue engineering applications. ASCs exhibit stable growth and proliferation in vitro and they possess ... -
Enterovirus localization in the spleen : detection of multiple targets within a single tissue section
(2019)
Pro gradu -tutkielmaTIIVISTELMÄ Enteroviruksien sijainnit pernassa – Monien markkerien havaitseminen Tutkielman tausta ja tavoitteet: Immunofluoresenssivärjäyksessä käytetään fluoresoivia vasta-aineita antigeenien värjäämiseen. Fluoresoivat ...
