Trepo - Selaus tekijän mukaan "Nättinen, Janika"
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Age-associated changes in human tear proteome
Nättinen, Janika; Jylhä, Antti; Aapola, Ulla; Mäkinen, Petri; Beuerman, Roger; Pietilä, Juhani; Vaajanen, Anu; Uusitalo, Hannu (2019)
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Clinical Tear Fluid Proteomics: A Novel Tool in Glaucoma Research
Nättinen, Janika; Aapola, Ulla; Nukareddy, Praveena; Uusitalo, Hannu (2022)
reviewarticleTear fluid forms the outermost layer of the ocular surface and its characteristics and composition have been connected to various ocular surface diseases. As tear proteomics enables the non-invasive investigation of protein ... -
Comparative proteomic analysis of human embryonic stem cell-derived and primary human retinal pigment epithelium
Hongisto, Heidi; Jylhä, Antti; Nättinen, Janika; Rieck, Jochen; Ilmarinen, Tanja; Veréb, Zoltán; Aapola, Ulla; Beuerman, Roger; Petrovski, Goran; Uusitalo, Hannu; Skottman, Heli (2017)
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Comparative proteomics reveals human pluripotent stem cell-derived limbal epithelial stem cells are similar to native ocular surface epithelial cells
Mikhailova, Alexandra; Jylhä, Antti; Rieck, Jochen; Nättinen, Janika; Ilmarinen, Tanja; Veréb, Zoltán; Aapola, Ulla; Beuerman, Roger; Petrovski, Goran; Uusitalo, Hannu; Skottman, Heli (2015)
articleLimbal epithelial stem cells (LESCs) are tissue-specific stem cells responsible for renewing the corneal epithelium. Acute trauma or chronic disease affecting LESCs may disrupt corneal epithelial renewal, causing vision ... -
Comparison of capillary and schirmer strip tear fluid sampling methods using swath-ms proteomics approach
Nättinen, Janika; Aapola, Ulla; Jylhä, Antti; Vaajanen, Anu; Uusitalo, Hannu (2020)
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Comparison of early changes in tear film protein profiles after small incision lenticule extraction (SMILE) and femtosecond LASIK (FS-LASIK) surgery
Mäkinen, Petri; Nättinen, Janika; Aapola, Ulla; Pietilä, Juhani; Uusitalo, Hannu (2024)
articleBackground: Small incision lenticule extraction (SMILE) and femtosecond laser-assisted in situ keratomileusis (LASIK) are widely used surgical methods to correct myopia with comparable efficacy, predictability, and safety. ... -
Comparison of iTRAQ and SWATH in a clinical study with multiple time points
Jylhä, Antti; Nättinen, Janika; Aapola, Ulla; Mikhailova, Alexandra; Nykter, Matti; Zhou, Lei; Beuerman, Roger; Uusitalo, Hannu (2018)
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Direct and indirect costs associated with declining distance visual acuity: A nationwide longitudinal cost-of-illness study with 11-year follow-up
Taipale, Joonas; Purola, Petri; Nättinen, Janika; Väätäinen, Saku; Koskinen, Seppo; Uusitalo, Hannu (2026)
articlePurpose: To examine the direct and indirect costs associated with declining distance visual acuity (VA). Methods: A longitudinal approach was applied to a large, nationally representative sample with extensive data, including ... -
Early changes in tear film protein profiles after femtosecond LASIK surgery
Nättinen, Janika; Mäkinen, Petri; Aapola, Ulla; Orsila, Lasse; Pietilä, Juhani; Uusitalo, Hannu (19.10.2020)
articleBackground: Femtosecond laser-assisted in situ keratomileusis (LASIK) has proven to be an efficacious, predictable, and safe procedure for the correction of refractive errors. We examined the early tear protein changes of ... -
Effects of Preserved and Preservative-Free Glaucoma Drugs on Proteomic Expression Levels in Corneal and Conjunctival Epithelial Cells in vitro
Nättinen, Janika (2015)
Pro gradu -tutkielma -
Impact of signs and symptoms of dry eye disease on health-related quality of life: a cross-sectional population study among older adults
Aapola, Ulla; Mosallaei, Paula; Nättinen, Janika; Suurkuukka, Ilona; Tuomilehto, Jaakko; Keinänen-Kiukaanniemi, Sirkka; Saramies, Jouko; Uusitalo, Hannu (2025)
articlePurpose: To assess the relationship between quality of life (QoL) and ocular surface health within a Finnish population-based cohort. Methods: A cross-sectional study involved 601 individuals born between the years 1933–1956. ... -
In vitrostem cell modelling demonstrates a proof-of-concept for excess functional mutant TIMP3 as the cause of Sorsbyfundusdystrophy
Hongisto, Heidi; Uusitalo, Hannu; Kaarniranta, Kai; Ratnayaka, J. Arjuna; Skottman, Heli; Lotery, Andrew J.; Dewing, Jennifer M.; Christensen, David R. G.; Scott, Jennifer; Cree, Angela J.; Nättinen, Janika; Määttä, Juha; Jylhä, Antti; Aapola, Ulla (2020)
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Integrative proteomics in prostate cancer uncovers robustness against genomic and transcriptomic aberrations during disease progression
Latonen, Leena; Afyounian, Ebrahim; Jylhä, Antti; Nättinen, Janika; Aapola, Ulla; Annala, Matti; Kivinummi, Kati; Tammela, Teuvo; Beuerman, Roger; Uusitalo, Hannu; Nykter, Matti; Visakorpi, Tapio (2018)
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Long noncoding RNA EPCART regulates translation through PI3K/AKT/mTOR pathway and PDCD4 in prostate cancer
Kohvakka, Annika; Sattari, Mina; Nättinen, Janika; Aapola, Ulla; Gregorová, Pavlína; Tammela, Teuvo L.J.; Uusitalo, Hannu; Sarin, L. Peter; Visakorpi, Tapio; Latonen, Leena (2024)
articleWhile hundreds of cancer-associated long noncoding RNAs (lncRNAs) have been discovered, their functional role in cancer cells is still largely a mystery. An increasing number of lncRNAs are recognized to function in the ... -
Looking deeper into ocular surface health: an introduction to clinical tear proteomics analysis
Nättinen, Janika; Aapola, Ulla; Nukareddy, Praveena; Uusitalo, Hannu (2021)
reviewarticleOcular surface diseases are becoming more prevalent worldwide. Reasons for this include the ongoing population ageing and increasing use of digital displays, although ophthalmologists have a wide selection of tools, which ... -
Low vision status and declining vision decrease Health-Related Quality of Life : Results from a nationwide 11-year follow-up study
Taipale, Joonas; Mikhailova, Alexandra; Ojamo, Matti; Nättinen, Janika; Väätäinen, Saku; Gissler, Mika; Koskinen, Seppo; Rissanen, Harri; Sainio, Päivi; Uusitalo, Hannu (2019)
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Microseminoprotein-Beta Expression in Different Stages of Prostate Cancer
Sjöblom, Liisa; Saramäki, Outi; Leinonen, Katri; Nättinen, Janika; Tolonen, Teemu; Wahlfors, Tiina; Nykter, Matti; Bova, Stephen G; Schleutker, Johanna; Tammela, Teuvo; Lilja, Hans; Visakorpi, Tapio (2016)
articleMicroseminoprotein-beta (MSMB, MSMB) is an abundant secretory protein contributed by the prostate, and is implicated as a prostate cancer (PC) biomarker based on observations of its lower expression in cancerous cells ... -
Monimuotoinen kuivasilmäisyys
Uusitalo, Hannu; Nättinen, Janika; Aapola, Ulla (2022)
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Ocular surface health of the Finnish elderly population
Aapola, Ulla; Nättinen, Janika; Suurkuukka, Ilona; Tuomilehto, Jaakko; Keinänen-Kiukaanniemi, Sirkka; Saramies, Jouko; Uusitalo, Hannu (2022)
articlePurpose: The aim of this study was to describe the clinical ocular surface characteristics in a population-based sample of Finnish elderly people. Methods: This cross-sectional study included 601 subjects (335 females, 266 ... -
Patient satisfaction and self-reported dry eye symptoms in hyperopic patients treated with femtosecond laser in situ keratomileusis
Mäkinen, Petri; Huhtala, Anne; Pietilä, Juhani; Nättinen, Janika; Rajala, Teppo; Salmenhaara, Kalle; Udratov, Magomed; Uusitalo, Hannu (2019)
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