Trepo - Selaus tekijän mukaan "Ma, Xiangmei"
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Estimation of the primary, secondary and composite effects of malaria vaccines using data on multiple clinical malaria episodes
Cheung, Yin Bun; Ma, Xiangmei; Lam, K.F.; Milligan, Paul (2020)
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Estimation of trajectory of protective efficacy in infectious disease prevention trials using recurrent event times
Cheung, Yin Bun; Ma, Xiangmei; Lam, K. F.; Yung, Chee Fu; Milligan, Paul (04 / 2024)
article<p>In studies of infectious disease prevention, the level of protective efficacy of medicinal products such as vaccines and prophylactic drugs tends to vary over time. Many products require administration of multiple doses ... -
Inclusion of unexposed clusters improves the precision of fixed effects analysis of stepped-wedge cluster randomized trials
Lee, Kenneth Menglin; Ma, Xiangmei; Yang, Grace Meijuan; Cheung, Yin Bun (2022)
article<p>Stepped-wedge cluster randomized trials (SW-CRTs) are typically analyzed using mixed effects models. The fixed effects model is a useful alternative that controls for all time-invariant cluster-level confounders and has ... -
Inclusion of unexposed subjects improves the precision and power of self-controlled case series method
Ma, Xiangmei; Lam, K. F.; Cheung, Yin Bun (11 / 2021)
article<p>The self-controlled case series is an important method in the studies of the safety of biopharmaceutical products. It uses the conditional Poisson model to make comparison within persons. In models without adjustment ... -
Modelling non-linear patterns of time-varying intervention effects on recurrent events in infectious disease prevention studies
Cheung, Yin Bun; Ma, Xiangmei; Lam, K. F.; Yung, Chee Fu; Milligan, Paul (10.08.2022)
article<p>Protective efficacy of vaccines and pharmaceutical products for prevention of infectious diseases usually vary over time. Information on the trajectory of the level of protection is valuable. We consider a parsimonious, ... -
Ratio estimators of intervention effects on event rates in cluster randomized trials
Ma, Xiangmei; Milligan, Paul; Lam, Kwok Fai; Cheung, Yin Bun (15.01.2021)
article<p>We consider five asymptotically unbiased estimators of intervention effects on event rates in non-matched and matched-pair cluster randomized trials, including ratio of mean counts (Formula presented.), ratio of mean ... -
Reverse Time-to-Death as Time-Scale in Time-to-Event Analysis for Studies of Advanced Illness and Palliative Care
Cheung, Yin Bun; Ma, Xiangmei; Chaudhry, Isha; Liu, Nan; Zhuang, Qingyuan; Yang, Grace Meijuan; Malhotra, Chetna; Finkelstein, Eric Andrew (10.02.2025)
article<p>Incidence of adverse outcome events rises as patients with advanced illness approach end-of-life. Exposures that tend to occur near end-of-life, for example, use of wheelchair, oxygen therapy and palliative care, may ... -
Two assumptions of the prior event rate ratio approach for controlling confounding can be evaluated by self-controlled case series and dynamic random intercept modeling
Cheung, Yin Bun; Ma, Xiangmei; Mackenzie, Grant (11 / 2024)
article<p>Objectives: The prior event rate ratio (PERR) is a recently developed approach for controlling confounding by measured and unmeasured covariates in real-world evidence research and observational studies. Despite its ...