Trepo - Selaus tekijän mukaan "Hurme, Mikko A."

Viitteet 1-4 / 4

    • DNA methylation signature of chronic low-grade inflammation and its role in cardio-respiratory diseases 

      Wielscher, Matthias; Mandaviya, Pooja R.; Kuehnel, Brigitte; Joehanes, Roby; Mustafa, Rima; Robinson, Oliver; Zhang, Yan; Bodinier, Barbara; Walton, Esther; Mishra, Pashupati P.; Schlosser, Pascal; Wilson, Rory; Tsai, Pei Chien; Palaniswamy, Saranya; Marioni, Riccardo E.; Fiorito, Giovanni; Cugliari, Giovanni; Karhunen, Ville; Ghanbari, Mohsen; Psaty, Bruce M.; Loh, Marie; Bis, Joshua C.; Lehne, Benjamin; Sotoodehnia, Nona; Deary, Ian J.; Chadeau-Hyam, Marc; Brody, Jennifer A.; Cardona, Alexia; Selvin, Elizabeth; Smith, Alicia K.; Miller, Andrew H.; Torres, Mylin A.; Marouli, Eirini; Gào, Xin; van Meurs, Joyce B.J.; Graf-Schindler, Johanna; Rathmann, Wolfgang; Koenig, Wolfgang; Peters, Annette; Weninger, Wolfgang; Farlik, Matthias; Zhang, Tao; Chen, Wei; Xia, Yujing; Teumer, Alexander; Nauck, Matthias; Grabe, Hans J.; Lehtimäki, Terho; Hurme, Mikko A.; Kähönen, Mika (03.05.2022)
      article
      We performed a multi-ethnic Epigenome Wide Association study on 22,774 individuals to describe the DNA methylation signature of chronic low-grade inflammation as measured by C-Reactive protein (CRP). We find 1,511 independent ...

    • Epigenome-wide association study of serum urate reveals insights into urate co-regulation and the SLC2A9 locus 

      Tin, Adrienne; Schlosser, Pascal; Matias-Garcia, Pamela R.; Thio, Chris H.L.; Joehanes, Roby; Liu, Hongbo; Yu, Zhi; Weihs, Antoine; Hoppmann, Anselm; Grundner-Culemann, Franziska; Min, Josine L.; Kuhns, Victoria L.Halperin; Adeyemo, Adebowale A.; Agyemang, Charles; Ärnlöv, Johan; Aziz, Nasir A.; Baccarelli, Andrea; Bochud, Murielle; Brenner, Hermann; Bressler, Jan; Breteler, Monique M.B.; Carmeli, Cristian; Chaker, Layal; Coresh, Josef; Corre, Tanguy; Correa, Adolfo; Cox, Simon R.; Delgado, Graciela E.; Eckardt, Kai Uwe; Ekici, Arif B.; Endlich, Karlhans; Floyd, James S.; Fraszczyk, Eliza; Gao, Xu; Gào, Xīn; Gelber, Allan C.; Ghanbari, Mohsen; Ghasemi, Sahar; Gieger, Christian; Greenland, Philip; Grove, Megan L.; Harris, Sarah E.; Hemani, Gibran; Henneman, Peter; Herder, Christian; Horvath, Steve; Hou, Lifang; Hurme, Mikko A.; Lehtimäki, Terho; Mishra, Pashupati P. (12 / 2021)
      article
      Elevated serum urate levels, a complex trait and major risk factor for incident gout, are correlated with cardiometabolic traits via incompletely understood mechanisms. DNA methylation in whole blood captures genetic and ...

    • Meta-analyses identify DNA methylation associated with kidney function and damage 

      Schlosser, Pascal; Tin, Adrienne; Matias-Garcia, Pamela R.; Thio, Chris H.L.; Joehanes, Roby; Liu, Hongbo; Weihs, Antoine; Yu, Zhi; Hoppmann, Anselm; Grundner-Culemann, Franziska; Min, Josine L.; Adeyemo, Adebowale A.; Agyemang, Charles; Ärnlöv, Johan; Aziz, Nasir A.; Baccarelli, Andrea; Bochud, Murielle; Brenner, Hermann; Breteler, Monique M.B.; Carmeli, Cristian; Chaker, Layal; Chambers, John C.; Cole, Shelley A.; Coresh, Josef; Corre, Tanguy; Correa, Adolfo; Cox, Simon R.; de Klein, Niek; Delgado, Graciela E.; Domingo-Relloso, Arce; Eckardt, Kai Uwe; Ekici, Arif B.; Endlich, Karlhans; Evans, Kathryn L.; Floyd, James S.; Fornage, Myriam; Franke, Lude; Fraszczyk, Eliza; Gao, Xu; Gào, Xīn; Ghanbari, Mohsen; Ghasemi, Sahar; Gieger, Christian; Greenland, Philip; Grove, Megan L.; Harris, Sarah E.; Hemani, Gibran; Hurme, Mikko A.; Lehtimäki, Terho; Mishra, Pashupati P. (12 / 2021)
      article
      Chronic kidney disease is a major public health burden. Elevated urinary albumin-to-creatinine ratio is a measure of kidney damage, and used to diagnose and stage chronic kidney disease. To extend the knowledge on regulatory ...

    • Meta-analysis of epigenome-wide association studies of carotid intima-media thickness 

      Portilla-Fernández, Eliana; Hwang, Shih Jen; Wilson, Rory; Maddock, Jane; Hill, W. David; Teumer, Alexander; Mishra, Pashupati P.; Brody, Jennifer A.; Joehanes, Roby; Ligthart, Symen; Ghanbari, Mohsen; Kavousi, Maryam; Roks, Anton J.M.; Danser, A. H.Jan; Levy, Daniel; Peters, Annette; Ghasemi, Sahar; Schminke, Ulf; Dörr, Marcus; Grabe, Hans J.; Lehtimäki, Terho; Kähönen, Mika; Hurme, Mikko A.; Bartz, Traci M.; Sotoodehnia, Nona; Bis, Joshua C.; Thiery, Joachim; Koenig, Wolfgang; Ong, Ken K.; Bell, Jordana T.; Meisinger, Christine; Wardlaw, Joanna M.; Starr, John M.; Seissler, Jochen; Then, Cornelia; Rathmann, Wolfgang; Ikram, M. Arfan; Psaty, Bruce M.; Raitakari, Olli T.; Völzke, Henry; Deary, Ian J.; Wong, Andrew; Waldenberger, Melanie; O’Donnell, Christopher J.; Dehghan, Abbas (2021)
      article
      <p>Common carotid intima-media thickness (cIMT) is an index of subclinical atherosclerosis that is associated with ischemic stroke and coronary artery disease (CAD). We undertook a cross-sectional epigenome-wide ...