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    • AXL-TBK1 driven AKT3 activation promotes metastasis 

      Arner, Emily N.; Alzhanova, Dina; Westcott, Jill M.; Hinz, Stefan; Tiron, Crina Elena; Blø, Magnus; Mai, Anja; Virtakoivu, Reetta; Phinney, Natalie; Nord, Silje; Aguilera, Kristina Y.; Rizvi, Ali; Toombs, Jason E.; Reese, Tanner C.; Fey, Vidal; Micklem, David; Gausdal, Gro; Ivaska, Johanna; Lorens, James B.; Brekken, Rolf A. (17.12.2024)
      article
      The receptor tyrosine kinase AXL promotes tumor progression, metastasis, and therapy resistance through the induction of epithelial-mesenchymal transition (EMT). Here, we found that activation of AXL resulted in the ...