Trepo - Selaus tiedekunnan mukaan (- 2018)
Viitteet 1-20 / 160
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Adipose stem cells and structural composites in the engineering of vascularized bone tissue
(2013)
Pro gradu -tutkielma -
Adult zebrafish model for studying DNA-based vaccination against mycobacterial disease
(2011)
Pro gradu -tutkielma -
Aggregation prediction; A bioinformatics method for studying the effects of missense variations on pathogenicity
(2012)
Pro gradu -tutkielmaBackground and Aims: Aggregation has been shown to be an intrinsic property of many proteins including proteins not involved in amyloid diseases. The most common types of protein aggregates are amyloid fibrils and amorphous ... -
All Titanium Microelectrode Array for Field Potential Measurements from Neurons and Cardiomyocytes: A Feasibility Study
(2011)
articleAbstract: In this paper, we describe our all-titanium microelectrode array (tMEA) fabrication process and show that uncoated titanium microelectrodes are fully applicable to measuring field potentials (FPs) from neurons ... -
Alternative Oxidase Expression in the Mouse Enables Bypassing Cytochrome c Oxidase Blockade and Limits Mitochondrial ROS Overproduction
(2013)
articleCyanide-resistant non-phosphorylating respiration is known in mitochondria from plants, fungi, and microorganisms but is absent in mammals. It results from the activity of an alternative oxidase (AOX) that conveys electrons ... -
Analysis of 953 Human Proteins from a Mitochondrial HEK293 Fraction by Complexome Profiling
(2013)
articleComplexome profiling is a novel technique which uses shotgun proteomics to establish protein migration profiles from fractionated blue native electrophoresis gels. Here we present a dataset of blue native electrophoresis ... -
Analysis of and prognostic information from disseminated tumour cells in bone marrow in primary breast cancer: a prospective observational study
(2012)
articleBackground Disseminated tumour cells (DTCs) in the bone marrow of patients with breast cancer have been identified as an independent predictor of poor prognosis in patients with non-metastatic disease. This prospective ... -
Analysis of BMP4 and BMP7 signaling in breast cancer cells unveils time-dependent transcription patterns and highlights a common synexpression group of gene
(2011)
articleBackground Bone morphogenetic proteins (BMPs) are members of the TGF-beta superfamily of growth factors. They are known for their roles in regulation of osteogenesis and developmental processes and, in recent years, ... -
Analysis of carbonic anhydrase related proteins VIII, X, and XI
(2011)
Pro gradu -tutkielmaBackground and Aims: Carbonic anhydrases (CAs) occur abundantly in nature and are found in many organisms which participate in many biologically important processes. Among the -CA gene family, there are three homologues ... -
Analysis of evolutionary pressure and pathogenicity of missense variations
(2012)
Pro gradu -tutkielmaBackground and aims: Gene and protein sequences are subject to variation upon reproduction where favorable alleles are expressed in further generations by positive selection and bad alleles are being eliminated by means ... -
Analysis of Jak2 Catalytic Function by Peptide Microarrays: The Role of the JH2 Domain and V617F Mutation
(2011)
articleJanus kinase 2 (JAK2) initiates signaling from several cytokine receptors and is required for biological responses such as erythropoiesis. JAK2 activity is controlled by regulatory proteins such as Suppressor of Cytokine ... -
Analysis of nucleotide repeats at variation sites
(2012)
Pro gradu -tutkielmaAbstract Background and aims:Nucleotide repeats are sequences that are repeated two or more times in the genome. They are generally classified into two broad groups as tandem repeats or dispersed repeats. They can be found ... -
Analysis of regulated genes of BMP4 signaling in breast cancer cell lines
(2013)
Pro gradu -tutkielmaBackground and aim: The role of bone morphogenetic proteins (BMP) 4 and 7 in primary breast cancer is peculiar as they are known to induce cell proliferation in some tumor cells and also to reduce tumor growth in some ... -
Analysis of Replication Intermediates Indicates That Drosophila melanogaster Mitochondrial DNA Replicates by a Strand-Coupled Theta Mechanism
(2013)
articleMitochondrial DNA synthesis is necessary for the normal function of the organelle and for the eukaryotic organism as a whole. Here we demonstrate, using two-dimensional agarose gel electrophoresis to analyse replication ... -
Analysis of variation site in post-translational modification
(2013)
Pro gradu -tutkielmaPost-translational modification (PTM) is a modification of a protein after its translation. This modification can occur either by the covalent addition of particular chemical groups or by enzymatic cleavage of peptide bond. ... -
Analysis of Xq27-28 linkage in the international consortium for prostate cancer genetics (ICPCG) families
(2012)
articleBackground Genetic variants are likely to contribute to a portion of prostate cancer risk. Full elucidation of the genetic etiology of prostate cancer is difficult because of incomplete penetrance and genetic and ... -
Applying genome-wide approach to define the genetics of low-density lipoprotein oxidation in two large cohorts
(2013)
Pro gradu -tutkielmaBackground: Cardiovascular diseases (CVD) are the number one killer and cause of disability in today’s world. Oxidized low-density lipoprotein (oxLDL) is considered to be a key factor in the development of atherosclerosis ... -
ARLTS1 and Prostate Cancer Risk - Analysis of Expression and Regulation
(2013)
articleProstate cancer (PCa) is a heterogeneous trait for which several susceptibility loci have been implicated by genome-wide linkage and association studies. The genomic region 13q14 is frequently deleted in tumour tissues of ... -
Assessing the Immunogenicity of GTU®-based HIV-1 Multigene DNA Vaccines in Murine Models
Acta Electronica Universitatis Tamperensis : 1082 (Tampere University Press, 2011)
VäitöskirjaVäitöskirjatyössä arvioitiin alun perin Tampereen yliopistossa ja myöhemmin FIT Biotech Oy:ssä kehitetyn HIV-1 rokotteen tehoa ja kykyä synnyttää HIV-spesifinen suojaava immuunivaste hiirimalleissa. Terapeuttisen HIV-1 ... -
B-Trikalsiumfosfaattia (B-TCP) sisältävän, antibiootteja vapauttavan ja biohajoavan luun täytemateriaalin ominaisuuksien tutkimus
(2011)
Pro gradu -tutkielmaTutkimuksen tausta ja tavoitteet: Osteomyeliitti eli luumätä on bakteerien aiheuttama luukudoksen tuhoutumistauti, jossa patogeenejä on vaikea tuhota ja jonka jättämiä vaurioita voidaan nykyään etupäässä hoitaa luusiirteillä ...
